Bardiya Zangbar, Nicole Lin, Aryan Rafieezadeh, Jordan Kirsch, Ilya Shnaydman, Lars Eckenberg, Gabriel Froula, Joshua Klein, Matthew Bronstein, Kartik Prabhakaran
{"title":"Obesity portends an increased risk of thromboembolic events in severely injured geriatric trauma, a retrospective study.","authors":"Bardiya Zangbar, Nicole Lin, Aryan Rafieezadeh, Jordan Kirsch, Ilya Shnaydman, Lars Eckenberg, Gabriel Froula, Joshua Klein, Matthew Bronstein, Kartik Prabhakaran","doi":"10.1016/j.amjsurg.2024.116139","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Obesity is a known risk factor for thromboembolic complications in trauma patients. The aim of our study is to evaluate the prevalence of thrombotic complications in obese geriatric patients.</p><p><strong>Methods: </strong>We performed a retrospective analysis of TQIP (2017-2019). A total of 119,906 patients≥65 years who sustained severe trauma were included. Primary outcomes were thrombotic complications including stroke/cerebrovascular accidents (CVA), myocardial infarction (MI), deep vein thrombosis (DVT) and pulmonary embolism (PE). Outcomes were compared between patients with obesity (BMI≥30 kg∖m<sup>2</sup>) and overweight (25 kg∖m<sup>2</sup>≤BMI<30 kg∖m<sup>2</sup>) and normal weight (19 kg∖m<sup>2</sup>≤BMI<25 kg∖m<sup>2</sup>) patients.</p><p><strong>Results: </strong>A total number of 30,356 (26.8 %) patients were obese. All clotting complications (stroke/CVA, MI, DVT and PE) were significantly more frequent among obese patients (p < 0.001for all). Multivariate logistic regression showed that obese patients had significantly increased odds of stroke/CVA (OR = 1.207), MI (OR = 1.301), DVT (OR = 1.311) and PE (OR = 1.241) (p < 0.001 for all).</p><p><strong>Conclusion: </strong>Obese geriatric patients who sustain severe traumatic injuries are at increased risk of thromboembolic complications compared to non-obese patients.</p><p><strong>Level of evidence: </strong>Level III retrospective study.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"116139"},"PeriodicalIF":2.7000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.amjsurg.2024.116139","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Obesity is a known risk factor for thromboembolic complications in trauma patients. The aim of our study is to evaluate the prevalence of thrombotic complications in obese geriatric patients.
Methods: We performed a retrospective analysis of TQIP (2017-2019). A total of 119,906 patients≥65 years who sustained severe trauma were included. Primary outcomes were thrombotic complications including stroke/cerebrovascular accidents (CVA), myocardial infarction (MI), deep vein thrombosis (DVT) and pulmonary embolism (PE). Outcomes were compared between patients with obesity (BMI≥30 kg∖m2) and overweight (25 kg∖m2≤BMI<30 kg∖m2) and normal weight (19 kg∖m2≤BMI<25 kg∖m2) patients.
Results: A total number of 30,356 (26.8 %) patients were obese. All clotting complications (stroke/CVA, MI, DVT and PE) were significantly more frequent among obese patients (p < 0.001for all). Multivariate logistic regression showed that obese patients had significantly increased odds of stroke/CVA (OR = 1.207), MI (OR = 1.301), DVT (OR = 1.311) and PE (OR = 1.241) (p < 0.001 for all).
Conclusion: Obese geriatric patients who sustain severe traumatic injuries are at increased risk of thromboembolic complications compared to non-obese patients.
期刊介绍:
The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.