Efficacy of the mHealth App Intellect in Improving Subclinical Obsessive-Compulsive Disorder in University Students: Randomized Controlled Trial With a 4-Week Follow-Up.

IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES JMIR mHealth and uHealth Pub Date : 2024-12-16 DOI:10.2196/63316
Madeline Lee Yoon Li, Stephanie Lee Si Min, Oliver Sündermann
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Abstract

Background: Obsessive-compulsive disorder (OCD) is the third most prevalent mental health disorder in Singapore, with a high degree of burden and large treatment gaps. Self-guided programs on mobile apps are accessible and affordable interventions, with the potential to address subclinical OCD before symptoms escalate.

Objective: This randomized controlled trial aimed to examine the efficacy of a self-guided OCD program on the mobile health (mHealth) app Intellect in improving subclinical OCD and maladaptive perfectionism (MP) as a potential moderator of this predicted relationship.

Methods: University students (N=225) were randomly assigned to an 8-day, self-guided app program on OCD (intervention group) or cooperation (active control). Self-reported measures were obtained at baseline, after the program, and at a 4-week follow-up. The primary outcome measure was OCD symptom severity (Obsessive Compulsive Inventory-Revised [OCI-R]). Baseline MP was assessed as a potential moderator. Depression, anxiety, and stress (Depression Anxiety and Stress Scales-21) were controlled for during statistical analyses.

Results: The final sample included 192 participants. The intervention group reported significantly lower OCI-R scores compared with the active control group after the intervention (partial eta-squared [ηp2]=0.031; P=.02) and at 4-week follow-up (ηp2=0.021; P=.044). A significant, weak positive correlation was found between MP and OCI-R levels at baseline (r=0.28; P<.001). MP was not found to moderate the relationship between condition and OCI-R scores at postintervention (P=.70) and at 4-week follow-up (P=.88).

Conclusions: This study provides evidence that the self-guided OCD program on the Intellect app is effective in reducing subclinical OCD among university students in Singapore. Future studies should include longer follow-up durations and study MP as a moderator in a broader spectrum of OCD symptom severity.

Trial registration: ClinicalTrials.gov NCT06202677; https://clinicaltrials.gov/study/NCT06202677.

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移动医疗应用程序 Intellect 在改善大学生亚临床强迫症方面的功效:随访四周的随机对照试验。
背景:强迫症(OCD)是新加坡第三大最常见的精神健康障碍,负担程度高,治疗差距大。移动应用程序上的自我指导程序是可访问且负担得起的干预措施,有可能在症状升级之前解决亚临床强迫症。目的:本随机对照试验旨在检验移动健康(mHealth)应用程序Intellect上的自我引导强迫症程序在改善亚临床强迫症和适应不良完美主义(MP)方面的疗效,作为这种预测关系的潜在调节因素。方法:将225名大学生随机分为两组,分别进行为期8天的强迫症自主引导应用程序治疗(干预组)和合作治疗(主动对照组)。自我报告测量在基线、项目结束后和4周随访时获得。主要结局指标为强迫症症状严重程度(强迫性量表修订[OCI-R])。基线MP被评估为潜在的调节因子。在统计分析中控制抑郁、焦虑和压力(抑郁焦虑和压力量表-21)。结果:最终样本包括192名参与者。干预组干预后OCI-R评分明显低于积极对照组(偏方差[ηp2]=0.031;P= 0.02)和随访4周时(ηp2=0.021;P = .044)。MP与基线时OCI-R水平呈显著的弱正相关(r=0.28;结论:本研究提供了证据,证明智力应用程序上的强迫症自我指导项目对减少新加坡大学生的亚临床强迫症是有效的。未来的研究应该包括更长的随访时间,并研究MP在更广泛的强迫症症状严重程度中的调节作用。试验注册:ClinicalTrials.gov NCT06202677;https://clinicaltrials.gov/study/NCT06202677。
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来源期刊
JMIR mHealth and uHealth
JMIR mHealth and uHealth Medicine-Health Informatics
CiteScore
12.60
自引率
4.00%
发文量
159
审稿时长
10 weeks
期刊介绍: JMIR mHealth and uHealth (JMU, ISSN 2291-5222) is a spin-off journal of JMIR, the leading eHealth journal (Impact Factor 2016: 5.175). JMIR mHealth and uHealth is indexed in PubMed, PubMed Central, and Science Citation Index Expanded (SCIE), and in June 2017 received a stunning inaugural Impact Factor of 4.636. The journal focusses on health and biomedical applications in mobile and tablet computing, pervasive and ubiquitous computing, wearable computing and domotics. JMIR mHealth and uHealth publishes since 2013 and was the first mhealth journal in Pubmed. It publishes even faster and has a broader scope with including papers which are more technical or more formative/developmental than what would be published in the Journal of Medical Internet Research.
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