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Features of Mobile Health Apps for Tobacco Cessation That Appeal to Black Adults Who Use Tobacco Products: Focus Group Study. 对使用烟草产品的黑人成年人有吸引力的戒烟移动健康应用程序的功能:焦点小组研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-06 DOI: 10.2196/63340
Sonia A Clark, Remi Philips, Christine E Kistler, Adam O Goldstein, Chineme Enyioha

Background: Mobile health (mHealth) interventions show promise in supporting tobacco cessation. However, Black adults who use tobacco products are not well represented in mHealth studies for tobacco cessation, and their preferred features of mHealth apps are not well known. Identifying types of mHealth app features for tobacco cessation preferred by Black adults is critical to developing a culturally adapted app, with increased uptake by the target population.

Objective: The goal of this study was to explore culturally relevant preferences for features of smoking cessation mHealth apps among Black adults who use tobacco products.

Methods: A comprehensive list of features of mHealth apps for tobacco cessation was developed based on previous research and a review of existing mHealth literature. Through a content analysis, this list was divided into subgroups and used to develop a focus group guide. We recruited participants from Instagram, a social media platform. Eligible focus group participants included people who reported current use of a tobacco product, identified as being African American or Black, were 21 years old or older, and had access to Wi-Fi or the internet. Participants had to indicate interest in the use of an mHealth app for tobacco cessation. Participants discussed their opinions about different app features, including what features they felt would increase the use of an app by Black adults. Recordings from the focus groups were transcribed and coded deductively and inductively. We conducted a thematic content analysis of the resulting transcripts.

Results: Forty adults aged 21-69 (mean 43, SD 13.6) years participated in 8 focus groups. Fifty-seven percent were female, and 88% endorsed current cigarette use. Four central themes that represented app features emerged. (1) Participants wanted representation and inclusivity through personalization and featuring people with similar lived experiences, including representative images and relevant health information. (2) Participants desired the app to feature a diversity of experiences such as testimonials from individuals from different backgrounds rather than solely focusing on racial identity or excessive targeting of the Black community. (3) Participants desired accountability through trusted connections with health care professionals and other support groups within the app, as well as app tracking capability. (4) Encouragement and motivation were more salient incentives than monetary rewards.

Conclusions: Black adults who use tobacco products prefer a tobacco cessation app with features that are inclusive, relatable, supportive, and motivating. These findings can serve as the groundwork for the development of an mHealth app that will appeal to Black adults, potentially leading to increased app use, successful cessation, and health equity.

背景:移动健康(mHealth)干预措施在支持戒烟方面显示出希望。然而,使用烟草产品的黑人成年人在戒烟的移动健康研究中并没有得到很好的代表,他们喜欢的移动健康应用程序的功能也不为人所知。确定黑人成年人喜欢的移动健康应用程序戒烟功能类型对于开发适应文化的应用程序至关重要,因为目标人群的接受程度越来越高。目的:本研究的目的是探索使用烟草产品的黑人成年人对戒烟移动健康应用程序功能的文化相关偏好。方法:基于先前的研究和对现有移动健康文献的回顾,开发了一份用于戒烟的移动健康应用程序的综合功能列表。通过内容分析,将此列表划分为子组,并用于开发焦点小组指南。我们从社交媒体平台Instagram上招募了参与者。合格的焦点小组参与者包括报告目前使用烟草产品的人,被确定为非洲裔美国人或黑人,年龄在21岁或以上,可以访问Wi-Fi或互联网。参与者必须表明对使用移动健康应用程序戒烟的兴趣。参与者讨论了他们对应用程序不同功能的看法,包括他们认为哪些功能会增加黑人成年人对应用程序的使用。对焦点小组的录音进行演绎和归纳转录和编码。我们对得到的笔录进行了主题内容分析。结果:40名年龄21-69岁的成年人(平均43岁,标准差13.6)参加8个焦点组。57%的人是女性,88%的人支持目前的吸烟习惯。代表应用程序功能的四个中心主题出现了。(1)参与者希望通过个性化呈现具有相似生活经历的人,包括代表性图像和相关健康信息,从而实现代表性和包容性。(2)参与者希望该应用程序具有多样性的经历,例如来自不同背景的个人的证词,而不是仅仅关注种族身份或过度针对黑人社区。(3)参与者希望通过与医疗保健专业人员和应用程序内其他支持小组的可靠联系以及应用程序跟踪功能来问责。(4)鼓励和激励是比金钱奖励更显著的激励因素。结论:使用烟草产品的黑人成年人更喜欢具有包容性、相关性、支持性和激励性的戒烟应用程序。这些发现可以作为开发移动健康应用程序的基础,该应用程序将吸引黑人成年人,可能导致应用程序的使用增加,成功戒烟和健康公平。
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引用次数: 0
Quality and Multifunctionality in Mobile Apps for Gestational Diabetes: Systematic App Review. 妊娠糖尿病手机应用程序的质量和多功能性:系统的应用程序评论。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-05 DOI: 10.2196/76862
Qimeng Zhao, Alison Cooke, Lishan Huang, Yimin Tang, Dawn Dowding

Background: The use of mobile health (mHealth) apps can assist with the management of gestational diabetes (GDM). Although a number of studies have demonstrated their efficacy in improving maternal-fetal outcomes, opinions differ regarding their usability and overall quality. Poorly designed apps, with ill-conceived features or inappropriate content, may pose a threat to patient safety. Nevertheless, very few studies provide in-depth evaluations of app design quality, and the diversity of features and techniques used remains insufficiently explored.

Objective: We aimed to evaluate the quality and multifunctionality of commercially available mHealth apps for GDM.

Methods: This is a systematic app review guided by the TECH (target user, evaluation focus, connectedness, and health domain) framework and the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 checklist. Searches were conducted on the Apple App Store and Google Play. Apps were screened by name, description, and full navigation to identify inclusions. The quality of the apps was evaluated using the Mobile App Rating Scale and IMS Institute for Healthcare Informatics Functionality Score. Multifunctionality of the apps was evaluated using the GDM-adapted features and techniques list developed from the App Behavior Change Scale, NICE (National Institute for Health and Care Excellence) 2015 guidelines, and previous studies. The general features list, which contains instruction, data security, customization, and technical issues, was derived from previous studies.

Results: The search (June 2024) identified 23 commercially available apps from UK app stores. The overall app quality was evaluated to be satisfactory (Mobile App Rating Scale: mean 4.0, SD 0.36; IMS Institute for Healthcare Informatics Functionality Score: mean 5.83, SD 3.03). The multifunctionality evaluation found that the apps had a mean of 17.95 and SD of 7.31 across all 45 items. Overall, our findings suggested that mHealth apps for GDM achieved a certain level of multifunctionality. However, their feature types and supporting digital techniques are relatively basic. The apps focused on education and managing blood glucose control rather than integrating other self-monitoring data and pregnancy-relevant management into their design. The digital techniques used to achieve these features included text and manual operation, rather than other automated features.

Conclusions: This is the first app review to consider the relationship between app features and usability for women with GDM. Future app development should integrate a wide range of pregnancy-relevant information and more automated features and use advanced digital techniques to enable a holistic digital solution for women with GDM.

背景:使用移动健康(mHealth)应用程序可以帮助管理妊娠糖尿病(GDM)。虽然许多研究已经证明了它们在改善母胎结局方面的功效,但关于它们的可用性和整体质量,意见不一。设计糟糕的应用程序,加上考虑不周的功能或不恰当的内容,可能会对患者安全构成威胁。然而,很少有研究对应用设计质量进行深入评估,而且对应用所使用的功能和技术的多样性仍未进行充分探索。目的:我们旨在评估市面上可用于GDM的移动健康应用程序的质量和多功能。方法:这是一项系统的应用程序审查,由TECH(目标用户、评估重点、连通性和健康领域)框架和PRISMA(系统审查和荟萃分析的首选报告项目)2020清单指导。在苹果应用商店和b谷歌Play上进行了搜索。应用程序通过名称、描述和完整导航进行筛选,以识别包含内容。应用程序的质量使用移动应用程序评级量表和IMS医疗保健信息学研究所功能评分进行评估。应用程序的多功能性通过应用程序行为改变量表、NICE(国家健康与护理卓越研究所)2015年指南和之前的研究开发的gdm适应功能和技术列表进行评估。包含指令、数据安全、定制和技术问题的一般特性列表源自先前的研究。结果:搜索(2024年6月)确定了23个来自英国应用商店的商业应用程序。应用程序总体质量评价为满意(移动应用程序评分:平均4.0,SD 0.36; IMS医疗保健信息研究所功能评分:平均5.83,SD 3.03)。多功能评估发现,这些应用程序在所有45个项目中的平均得分为17.95,标准差为7.31。总的来说,我们的研究结果表明,针对GDM的移动健康应用程序实现了一定程度的多功能。然而,它们的特征类型和支持的数字技术是相对基本的。这些应用程序专注于教育和管理血糖控制,而不是将其他自我监测数据和妊娠相关管理整合到它们的设计中。用于实现这些功能的数字技术包括文本和手动操作,而不是其他自动化功能。结论:这是第一个考虑GDM女性应用功能与可用性之间关系的应用评论。未来的应用程序开发应该集成广泛的怀孕相关信息和更多的自动化功能,并使用先进的数字技术,为患有GDM的女性提供全面的数字解决方案。
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引用次数: 0
Evaluating the Feasibility of an Electronic Patient-Reported Outcomes Platform Integrating Electronic Health Records and a Mobile Messaging App in Breast Cancer Radiotherapy: Retrospective Cross-Sectional Study. 评估整合电子健康记录和移动消息应用程序的电子患者报告结果平台在乳腺癌放疗中的可行性:回顾性横断面研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-05 DOI: 10.2196/67514
Jong Yun Baek, Haeyoung Kim, Won Kyung Cho, Nalee Kim, Tae Hoon Lee, Won Chul Cha
<p><strong>Background: </strong>Integrating electronic patient-reported outcomes (ePROs) into electronic health records (EHRs) can enhance the quality of patient care. However, collecting longitudinal ePRO data throughout treatment and posttreatment surveillance remains challenging in patients with breast cancer. To address this, we implemented an automated system that enables ePRO acquisition and seamless integration into the EHR. The system delivers questionnaire weblinks via a mobile messaging app, allowing patients to complete ePROs before clinic visits, with responses automatically transferred to the EHR.</p><p><strong>Objective: </strong>This study aimed to assess patient response rates to the ePRO system and identify key factors influencing the response rate among patients with breast cancer who received radiotherapy and postradiotherapy follow-up.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of prospectively collected ePRO data by using the BREAST-Q questionnaire, a validated patient-reported outcome measure for breast surgery, from patients who received adjuvant radiotherapy at our institution between May 2023 and April 2024. At a preradiotherapy or postradiotherapy visit, each patient was asked to complete the questionnaire via a weblink sent to their mobile messaging app, KakaoTalk. The questionnaire was dispatched from minutes to several days before each visit. The response rate was calculated as the percentage of patients whose responses were successfully recorded in the EHR among those who were requested to respond. A complete response (CR) was defined as completion of all required questionnaire items. CR rates were analyzed according to clinical factors using univariate and multivariate logistic regression.</p><p><strong>Results: </strong>Data from 1488 patients were analyzed, encompassing 2431 encounters (median 1, IQR 1-2 per patient). The median age of the patients was 51 (range 23-83) years, with 65.1% (n=968) patients aged 40 to 59 years. Comorbidities were present in 15% (223/1488) of the patients. The CR rate for the first, second, and third ePRO encounters was 89.9% (1338/1488), 98.3% (735/748), and 97.3% (180/185), respectively. Among first-time respondents, younger patients had a significantly higher CR rate (patients aged <60 years: 100/1104, 90.9%; patients aged ≥60 years: 334/384, 87%; P=.03). The timing of the questionnaire dispatch also affected the CR rate (P<.001). The CR rate was the highest when questionnaires were sent more than 1 hour before the visit (547/583, 93.3%) or in the afternoon of the previous day (505/545, 92.7%) and the lowest when sent 2 or more days before (100/130, 76.9%) or within 1 hour before the appointment (92/112, 81.7%). Both age (P=.006) and timing (P<.001) remained significant in the multivariate analysis.</p><p><strong>Conclusions: </strong>This study demonstrates the feasibility of integrating ePRO into EHR through a mobile messaging app-based system, with high
背景:将电子患者报告结果(ePROs)集成到电子健康记录(EHRs)中可以提高患者护理的质量。然而,在乳腺癌患者的整个治疗过程和治疗后监测中收集纵向ePRO数据仍然具有挑战性。为了解决这个问题,我们实施了一个自动化系统,可以获取ePRO并无缝集成到EHR中。该系统通过移动消息应用程序发送问卷链接,允许患者在就诊前完成电子病历,并将回复自动转移到电子病历中。目的:本研究旨在评估乳腺癌放疗及放疗后随访患者对ePRO系统的反应率,并确定影响反应率的关键因素。方法:我们对2023年5月至2024年4月期间在我院接受辅助放疗的患者进行回顾性分析,采用breast - q问卷(一种经过验证的患者报告的乳房手术结局测量方法)前瞻性收集的ePRO数据。在放疗前或放疗后的访问中,每位患者都被要求通过发送到他们的移动消息应用程序KakaoTalk的webblink完成问卷。问卷在每次访问前几分钟到几天分发。应答率计算为应答成功记录在电子病历中的患者在被要求应答的患者中的百分比。完整回答(CR)定义为完成所有要求的问卷项目。根据临床因素采用单因素和多因素logistic回归分析CR率。结果:分析了1488例患者的数据,包括2431次就诊(中位数1,IQR 1-2 /患者)。患者的中位年龄为51岁(23-83岁),其中65.1% (n=968)的患者年龄在40 - 59岁之间。15%(223/1488)的患者存在合并症。第一次、第二次和第三次ePRO就诊的CR率分别为89.9%(1338/1488)、98.3%(735/748)和97.3%(180/185)。结论:本研究证明了通过基于移动消息应用程序的系统将ePRO整合到电子病历中的可行性,且患者依从性高。应答率受患者年龄和问卷发放时间的显著影响。这些发现为优化ePRO在常规肿瘤护理中的实施提供了实用的见解。
{"title":"Evaluating the Feasibility of an Electronic Patient-Reported Outcomes Platform Integrating Electronic Health Records and a Mobile Messaging App in Breast Cancer Radiotherapy: Retrospective Cross-Sectional Study.","authors":"Jong Yun Baek, Haeyoung Kim, Won Kyung Cho, Nalee Kim, Tae Hoon Lee, Won Chul Cha","doi":"10.2196/67514","DOIUrl":"https://doi.org/10.2196/67514","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Integrating electronic patient-reported outcomes (ePROs) into electronic health records (EHRs) can enhance the quality of patient care. However, collecting longitudinal ePRO data throughout treatment and posttreatment surveillance remains challenging in patients with breast cancer. To address this, we implemented an automated system that enables ePRO acquisition and seamless integration into the EHR. The system delivers questionnaire weblinks via a mobile messaging app, allowing patients to complete ePROs before clinic visits, with responses automatically transferred to the EHR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to assess patient response rates to the ePRO system and identify key factors influencing the response rate among patients with breast cancer who received radiotherapy and postradiotherapy follow-up.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a retrospective analysis of prospectively collected ePRO data by using the BREAST-Q questionnaire, a validated patient-reported outcome measure for breast surgery, from patients who received adjuvant radiotherapy at our institution between May 2023 and April 2024. At a preradiotherapy or postradiotherapy visit, each patient was asked to complete the questionnaire via a weblink sent to their mobile messaging app, KakaoTalk. The questionnaire was dispatched from minutes to several days before each visit. The response rate was calculated as the percentage of patients whose responses were successfully recorded in the EHR among those who were requested to respond. A complete response (CR) was defined as completion of all required questionnaire items. CR rates were analyzed according to clinical factors using univariate and multivariate logistic regression.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Data from 1488 patients were analyzed, encompassing 2431 encounters (median 1, IQR 1-2 per patient). The median age of the patients was 51 (range 23-83) years, with 65.1% (n=968) patients aged 40 to 59 years. Comorbidities were present in 15% (223/1488) of the patients. The CR rate for the first, second, and third ePRO encounters was 89.9% (1338/1488), 98.3% (735/748), and 97.3% (180/185), respectively. Among first-time respondents, younger patients had a significantly higher CR rate (patients aged &lt;60 years: 100/1104, 90.9%; patients aged ≥60 years: 334/384, 87%; P=.03). The timing of the questionnaire dispatch also affected the CR rate (P&lt;.001). The CR rate was the highest when questionnaires were sent more than 1 hour before the visit (547/583, 93.3%) or in the afternoon of the previous day (505/545, 92.7%) and the lowest when sent 2 or more days before (100/130, 76.9%) or within 1 hour before the appointment (92/112, 81.7%). Both age (P=.006) and timing (P&lt;.001) remained significant in the multivariate analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study demonstrates the feasibility of integrating ePRO into EHR through a mobile messaging app-based system, with high","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"14 ","pages":"e67514"},"PeriodicalIF":6.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence of Efficacy of the My Personal Health Guide Mobile Phone App on Antiretroviral Therapy Adherence Among Young African American Men Who Have Sex With Men at 1 Month: Randomized Controlled Trial. “我的个人健康指南”手机应用程序对年轻非裔美国男男性行为者1个月抗逆转录病毒治疗依从性的疗效证据:随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-03 DOI: 10.2196/75005
Mark S Dworkin, Kara Herrera, Sierra Upton, Casey M Luc, Jeb Jones, Paul Burns, Li Liu, Antonio Jimenez, Ruiqi Ren, Meaghan Woody, Robert Garofalo, Sangyoon Lee
<p><strong>Background: </strong>Young African American men who have sex with men (AAMSM) experience disproportionately high HIV incidence and are less likely to achieve viral suppression compared to White men who have sex with men, an outcome that relies on antiretroviral therapy (ART) adherence. We created My Personal Health Guide, a talking relational agent-based mobile health app to improve ART adherence among young AAMSM.</p><p><strong>Objective: </strong>The objective was to determine the efficacy of My Personal Health Guide on improving ART adherence among young AAMSM living with HIV.</p><p><strong>Methods: </strong>We implemented a randomized controlled trial among young (aged 18-34 years) AAMSM with nonoptimal ART adherence throughout the United States between February 2020 and September 2023, predominantly through social media and by word of mouth, provider referral, and fliers in selected health care settings. Participants were randomized in a 1:1 ratio using permuted blocks of 8 to the intervention, My Personal Health Guide, or the attention control arm. ART adherence was assessed with Wilson's 3-item self-reported adherence measurement and dichotomized at ≥80%. Logistic regression models using backward selection were used to evaluate the efficacy of My Personal Health Guide on ≥80% ART adherence at 1-month follow-up.</p><p><strong>Results: </strong>Among the 253 AAMSM at baseline, most (n=180, 71.1%) self-reported being ≥80% adherent to ART, over half (n=145, 57.3%) resided in the Southern United States, but all US regions were represented, nearly half (n=175, 42.3%) had some college education, over one-third (n=96, 37.9%) had less than optimal literacy, and approximately one-quarter (n=61, 24.1%) experienced housing insecurity in the past 6 months. The sample for analysis of the My Personal Health Guide app efficacy was 131 (intervention=76 and control=55). The odds of being ≥80% adherent to ART at 1-month follow-up were 3.97 (95% CI 1.26-12.55) times greater among participants randomized to the My Personal Health Guide app compared to the controls, after adjusting for ART adherence at baseline, treatment adherence self-efficacy, and ever being incarcerated. Additionally, for every 1-point increase in the HIV Treatment Adherence Self-Efficacy Scale, the odds of ≥80% ART adherence increased by 3% (odds ratio 1.03, 95% CI 1.00-1.06).</p><p><strong>Conclusions: </strong>Participants randomized to receive My Personal Health Guide reported nearly 4 times greater odds of being ≥80% adherent to ART compared to the attention control group at 1-month follow-up. To our knowledge, this is the first randomized controlled trial demonstrating improved medication adherence using a relational agent-based behavioral intervention. These findings provide evidence of short-term efficacy of My Personal Health Guide to improve ART adherence among young AAMSM. We recommend further research on the inclusion of relational agents in behavioral research, espec
背景:年轻的非洲裔美国男男性行为者(AAMSM)经历了不成比例的高艾滋病毒发病率,与白人男男性行为者相比,病毒抑制的可能性更小,这一结果依赖于抗逆转录病毒治疗(ART)的坚持。我们创建了我的个人健康指南,这是一个会说话的基于关系代理的移动健康应用程序,旨在提高年轻的AAMSM对抗逆转录病毒治疗的依从性。目的:目的是确定我的个人健康指南在提高艾滋病毒感染的年轻男男性行为者抗逆转录病毒治疗依从性方面的功效。方法:我们在2020年2月至2023年9月期间在美国各地的非最佳ART依从性的年轻(18-34岁)AAMSM中实施了一项随机对照试验,主要通过社交媒体和口口相传,提供者推荐和选定医疗机构的传单。参与者以1:1的比例随机分配,使用8个排列块进行干预,我的个人健康指南或注意力控制臂。采用Wilson的3项自我报告依从性测量法评估ART依从性,并在≥80%时进行二分类。采用Logistic回归模型进行逆向选择,评估《我的个人健康指南》在随访1个月时ART依从性≥80%的疗效。结果:在基线的253名AAMSM中,大多数(n=180, 71.1%)自我报告的ART依从率≥80%,超过一半(n=145, 57.3%)居住在美国南部,但所有美国地区都有代表,近一半(n=175, 42.3%)接受过大学教育,超过三分之一(n=96, 37.9%)的识字率低于最佳水平,约四分之一(n=61, 24.1%)在过去6个月内经历过住房不安全。用于分析My Personal Health Guide应用程序功效的样本为131(干预=76,对照组=55)。在调整基线ART依从性、治疗依从性自我效能和曾经入狱后,随机分配到My Personal Health Guide应用程序的参与者在1个月随访时ART依从性≥80%的几率是对照组的3.97倍(95% CI 1.26-12.55)。此外,HIV治疗依从性自我效能量表每增加1分,ART依从性≥80%的几率增加3%(优势比1.03,95% CI 1.00-1.06)。结论:在1个月的随访中,随机接受“我的个人健康指南”的参与者报告的ART依从率≥80%的几率是注意力对照组的近4倍。据我们所知,这是第一个随机对照试验,证明使用基于关系代理的行为干预可以改善药物依从性。这些发现为“我的个人健康指南”提高年轻AAMSM的抗逆转录病毒治疗依从性的短期疗效提供了证据。我们建议进一步研究在行为研究中纳入关系因子,特别是在受污名和非最佳健康素养影响的人群中,这种非人类的支持和教育方法可能是卫生保健系统的补充。试验注册:ClinicalTrials.gov NCT04217174;https://clinicaltrials.gov/study/NCT04217174。
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引用次数: 0
A Finger on the Pulse of Happiness: A Pilot Study Assessing Mental Health Using Smartphone Photoplethysmography-Based Digital Pulse Waveform Analysis. 手指在幸福的脉搏上:一项利用智能手机光电脉搏波形分析评估心理健康的试点研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-02 DOI: 10.2196/81301
Ivan Liu, Luming Hu, Jing Luo, Chang Liu, Qi Zhong, Shiguang Ni
<p><strong>Background: </strong>Pulse characteristics are well-established biomarkers of physical health; however, their relevance to psychological well-being remains insufficiently explored. A key barrier is the difficulty of acquiring pulse recordings of adequate quality outside clinical or laboratory settings using accessible measurement approaches.</p><p><strong>Objective: </strong>This study aimed to examine the feasibility of using smartphone photoplethysmography (PPG) to extract fingertip pulse-waveform features and to evaluate their associations with psychological measures. It further aimed to systematically compare time-, curvature-, and frequency-domain pulse-waveform features in relation to psychological variables.</p><p><strong>Methods: </strong>A total of 127 students and university employees in Shenzhen, China, were recruited. Participants recorded repeated 4-minute fingertip videos using a custom smartphone application while an FDA-cleared fingertip oximeter simultaneously acquired reference pulse signals. Smartphone videos were converted into PPG signals, segmented into beat-to-beat intervals, and summarized into time-, curvature-, and frequency-domain features using median values, with normalization for heart rate and stature. Psychological well-being and mental health were assessed using the Satisfaction With Life Scale (SWLS), Subjective Vitality Scale (SVS), Positive and Negative Affect Schedule (PANAS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and the Self-Assessment Manikin (SAM). Associations between pulse-waveform features and psychological measures were examined using univariate regression with participant-level aggregation and cluster-robust standard errors. Random forest models evaluated multivariate predictive performance using participant-level cross-validation. Agreement between smartphone-derived and oximeter-derived waveform features was assessed using Bland-Altman analysis.</p><p><strong>Results: </strong>Correlation analyses revealed strong within-domain associations among time-, curvature-, and frequency-domain pulse-waveform features, with comparatively weaker cross-domain correlations. A correlation-based feature-selection procedure reduced multicollinearity and yielded a final set of seven features (ERI, CT, F/A, H/A, rPSD1, V0, and SBP). Univariate regression analyses indicated that negative psychological states were primarily associated with time- and curvature-domain features. Depressive symptoms were significantly related to F/A and V0, with ERI remaining significant after Bonferroni correction. Generalized anxiety showed a Bonferroni-corrected association with F/A, and negative affect was associated with CT and F/A. In contrast, positive affect measures showed fewer and weaker associations. Momentary valence was related to F/A and H/A, whereas arousal was associated with CT and H/A. Random forest models demonstrated statistically significant but modest predictive pe
背景:脉搏特征是公认的身体健康的生物标志物;然而,它们与心理健康的相关性仍未得到充分探讨。一个关键的障碍是难以在临床或实验室环境之外使用可获得的测量方法获得足够质量的脉搏记录。目的:探讨利用智能手机光体积脉搏波(PPG)提取指尖脉搏波形特征的可行性,并评价其与心理测量的相关性。它进一步旨在系统地比较时域、曲率和频域脉冲波形特征与心理变量的关系。方法:在中国深圳招募127名在校学生和高校职工。参与者使用定制的智能手机应用程序重复录制4分钟的指尖视频,同时fda批准的指尖血氧仪同时获取参考脉搏信号。将智能手机视频转换为PPG信号,分割成心跳间隔,并使用中位数将其总结为时间域、曲率域和频域特征,并将心率和身高归一化。采用生活满意度量表(SWLS)、主观活力量表(SVS)、积极和消极情绪量表(PANAS)、患者健康问卷-9 (PHQ-9)、广泛性焦虑障碍量表-7 (GAD-7)和自我评估模型(SAM)对心理健康和心理健康进行评估。脉冲波形特征与心理测量之间的关联采用参与者水平聚集和聚类鲁棒标准误差的单变量回归进行检验。随机森林模型使用参与者水平交叉验证评估多变量预测性能。使用Bland-Altman分析评估智能手机和血氧仪波形特征之间的一致性。结果:相关分析显示时域、曲率域和频域脉冲波形特征在域内具有很强的相关性,而跨域相关性相对较弱。基于相关性的特征选择程序减少了多重共线性,并产生了最终的7个特征集(ERI、CT、F/A、H/A、rPSD1、V0和SBP)。单因素回归分析表明,消极心理状态主要与时间和曲率域特征有关。抑郁症状与F/A和V0显著相关,经Bonferroni校正后ERI仍然显著。广泛性焦虑与F/ a呈bonferroni校正相关性,消极情绪与CT和F/ a相关。相比之下,积极影响测量显示出较少和较弱的关联。瞬时效价与F/A和H/A相关,而唤醒与CT和H/A相关。随机森林模型对消极心理健康结果的预测表现在统计上显著但适度,对积极心理健康结果的预测表现较弱。Bland-Altman分析表明,具有显著预测相关性的结果存在最小的系统偏倚。与fda批准的指尖血氧仪的比较显示出显著的相关性和可接受的一致性,时域特征显示出比基于反射的指标更强的稳健性。结论:基于智能手机的PPG可以捕获与心理测量相关的脉冲波形特征,尤其是消极的心理状态。然而,预测性能仍然有限,用户操作记录的信号质量变化带来了实际挑战。未来的研究需要纳入更多样化的样本,改进信号采集和纵向设计,以进一步评估这种方法在心理健康监测中的效用。临床试验:
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引用次数: 0
The Landscape of Mobile Apps for Healthy Eating: Case Study for a Systematic Review and Quality Assessment. 健康饮食的移动应用前景:系统审查和质量评估的案例研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-30 DOI: 10.2196/68737
Garlene Zamora Zamorano, Alejandro Déniz-García, Alezandra Torres-Castaño, María Luisa Álvarez-Malé, Inger Torhild Gram, Guri Skeie, Ana M Wägner

Background: Mobile apps are being increasingly used to foster healthy lifestyles. There is a growing need for clear, standardized guidelines to help users select safe and effective health apps.

Objective: Our study aimed to highlight the importance of establishing a structured framework for quality evaluation in mobile health (mHealth) through a case study of mobile apps promoting healthy eating.

Methods: We conducted a systematic review of apps promoting healthy eating that had already been evaluated by one or more of 28 recognized health app certification bodies. Three rounds of app evaluations were conducted by experts in nutrition and behavior change. The first two rounds focused on the quality of the content of the recommendations and were performed pairwise using the Quality Evaluation Scoring Tool (QUEST), which has not been previously used by the certification bodies. In addition, in the second and third rounds, each reviewer answered the question "How probable is it that you would recommend this app?" using a subjective scale score from 0 to 10. In the third round, this score was weighed by usability (30%), content quality (40%), and promotion of behavior change (30%). Discussions were held to resolve scoring discrepancies and to identify the top-quality apps. We also assessed correlations among QUEST, Google Play Store, and certification body scores.

Results: Of the 41 apps identified by five certification bodies, 19 (46.3%) met the inclusion criteria and were examined. Only 16 (84.2%) of these remained accessible for the second round. Eight of these surpassed 20 points (out of a maximum of 28) on the QUEST scale and were evaluated by all six experts in the third round, and the top 5 (62.5%) apps were selected. No correlations were found among QUEST, Google Play Store, and certification body scores.

Conclusions: Despite numerous evaluations by various certification bodies, only 5 (12.2%) of the 41 apps met the quality standards set by our experts. Our results mark the importance of rigorous, transparent, and standardized app evaluation processes to guide users toward making informed decisions about health apps. Guidelines for developers for the design of evidence-based, unbiased, high-quality apps, as well as technological solutions for real-time monitoring of the health apps, would address these challenges and improve reliability.

背景:人们越来越多地使用移动应用程序来培养健康的生活方式。越来越需要清晰、标准化的指导方针来帮助用户选择安全有效的健康应用程序。目的:我们的研究旨在通过对促进健康饮食的移动应用程序的案例研究,强调在移动健康(mHealth)中建立质量评估的结构化框架的重要性。方法:我们对28个公认的健康应用程序认证机构中的一个或多个评估过的促进健康饮食的应用程序进行了系统回顾。营养和行为改变方面的专家进行了三轮应用程序评估。前两轮侧重于建议内容的质量,并使用质量评估评分工具(QUEST)两两执行,该工具以前未被认证机构使用过。此外,在第二轮和第三轮中,每个评论者都用从0到10的主观评分来回答“你推荐这款应用的可能性有多大?”在第三轮中,这个分数由可用性(30%)、内容质量(40%)和行为改变的促进(30%)来衡量。讨论解决了评分差异,并确定了最高质量的应用程序。我们还评估了QUEST、谷歌Play Store和认证机构得分之间的相关性。结果:在5个认证机构确定的41个应用程序中,有19个(46.3%)符合纳入标准并进行了检查。其中只有16个(84.2%)可以进入第二轮。其中8个在QUEST量表上超过20分(最高28分),并由所有6位专家在第三轮进行评估,并选择前5名(62.5%)应用程序。QUEST、谷歌Play Store和认证机构得分之间没有相关性。结论:尽管各种认证机构进行了多次评估,但41个应用程序中只有5个(12.2%)符合我们专家设定的质量标准。我们的研究结果表明,严格、透明和标准化的应用程序评估过程对于指导用户对健康应用程序做出明智的决定非常重要。为开发者设计基于证据的、公正的、高质量的应用程序的指导方针,以及实时监控健康应用程序的技术解决方案,将解决这些挑战,提高可靠性。
{"title":"The Landscape of Mobile Apps for Healthy Eating: Case Study for a Systematic Review and Quality Assessment.","authors":"Garlene Zamora Zamorano, Alejandro Déniz-García, Alezandra Torres-Castaño, María Luisa Álvarez-Malé, Inger Torhild Gram, Guri Skeie, Ana M Wägner","doi":"10.2196/68737","DOIUrl":"https://doi.org/10.2196/68737","url":null,"abstract":"<p><strong>Background: </strong>Mobile apps are being increasingly used to foster healthy lifestyles. There is a growing need for clear, standardized guidelines to help users select safe and effective health apps.</p><p><strong>Objective: </strong>Our study aimed to highlight the importance of establishing a structured framework for quality evaluation in mobile health (mHealth) through a case study of mobile apps promoting healthy eating.</p><p><strong>Methods: </strong>We conducted a systematic review of apps promoting healthy eating that had already been evaluated by one or more of 28 recognized health app certification bodies. Three rounds of app evaluations were conducted by experts in nutrition and behavior change. The first two rounds focused on the quality of the content of the recommendations and were performed pairwise using the Quality Evaluation Scoring Tool (QUEST), which has not been previously used by the certification bodies. In addition, in the second and third rounds, each reviewer answered the question \"How probable is it that you would recommend this app?\" using a subjective scale score from 0 to 10. In the third round, this score was weighed by usability (30%), content quality (40%), and promotion of behavior change (30%). Discussions were held to resolve scoring discrepancies and to identify the top-quality apps. We also assessed correlations among QUEST, Google Play Store, and certification body scores.</p><p><strong>Results: </strong>Of the 41 apps identified by five certification bodies, 19 (46.3%) met the inclusion criteria and were examined. Only 16 (84.2%) of these remained accessible for the second round. Eight of these surpassed 20 points (out of a maximum of 28) on the QUEST scale and were evaluated by all six experts in the third round, and the top 5 (62.5%) apps were selected. No correlations were found among QUEST, Google Play Store, and certification body scores.</p><p><strong>Conclusions: </strong>Despite numerous evaluations by various certification bodies, only 5 (12.2%) of the 41 apps met the quality standards set by our experts. Our results mark the importance of rigorous, transparent, and standardized app evaluation processes to guide users toward making informed decisions about health apps. Guidelines for developers for the design of evidence-based, unbiased, high-quality apps, as well as technological solutions for real-time monitoring of the health apps, would address these challenges and improve reliability.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"14 ","pages":"e68737"},"PeriodicalIF":6.2,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod-Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial. 可穿戴设备增强患者监测/基于电生理豆荚的反馈对结直肠癌术后并发症的影响:随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-30 DOI: 10.2196/70534
Yang Meng, Fengyan Fan, Yumei Ma, Nong Yan, Huan Wang, Zhen Zhang, Yiting Wang, Hailong Dong, Huang Nie

Background: Enhanced recovery after surgery (ERAS) guidelines recommend early postoperative mobilization to reduce complications, but adherence is often suboptimal, highlighting the need for effective tools to monitor and encourage movement. The Mindray enhanced patient monitoring (ePM)/electrophysiology (ep) pod, capable of tracking activity, vital signs, sleep, and pain, offers high-precision postoperative monitoring and is well-suited for research on activity feedback.

Objective: The study aims to assess whether wearable device-based (ePM/ep pod) activity feedback could reduce postoperative complications within 30 days of colorectal cancer (CRC) surgery.

Methods: We conducted an open-label, evaluator-blind, randomized controlled trial involving patients aged ≥18 years scheduled for CRC surgery. Patients were randomized to a feedback group or a control group. Both groups were set the same target activity time postoperatively based on ERAS guidelines. The feedback group received real-time visual feedback of movement time daily through the ePM/ep pod device, while the control group did not receive feedback. The primary outcome was the comprehensive complication index (CCI) within postoperative 30 days. Secondary outcomes included daily activity time, pain Numeric Rating Scale scores for rest and movement during the first 3 postoperative days, length of stay, percentage of reaching the scheduled mobilization target, 30-day postoperative mortality rate, and the times of first exhaust and defecation.

Results: Two hundred thirty-nine patients were recruited between February 2023 and September 2023, with 216 randomized (n=108 for each group). There was no significant difference in CCI within 30 postoperative days between the control group (median CCI 0, range 0-20.90) and the activity feedback group (median CCI 0, range 0-12.20). The estimated mean difference was -0.59 (95% CI -3.56 to 2.38; P=.66). Sensitivity analysis excluding patients with low device compliance did not alter these findings. No significant differences between groups were found in daily activity time, length of hospital stay, or pain scores. Post hoc analysis revealed significant negative correlations between 30-day CCI and activity on the second day after operation (r=-0.166) and the third day after operation (POD3) (r=-0.264; P<.05 for both). Linear regression indicated that POD3 activity significantly reduced CCI (β=-.025; 95% CI -0.045 to -0.006; P=.01), with peak CCI reduction at 215 minutes of activity.

Conclusions: In the context of ERAS, this study found no evidence that activity stimulation based on feedback from the wearable device (ePM/ep pod) could reduce 30-day postoperative CCI in patients undergoing CRC surgery. However, the ePM/ep pod could accurately record daily activity duration, which may be negatively correlated with CCI on POD3.

背景:加强术后恢复(ERAS)指南建议术后早期活动以减少并发症,但依从性往往不是最佳的,强调需要有效的工具来监测和鼓励活动。迈瑞增强型患者监测(ePM)/电生理(ep)吊舱,能够跟踪活动、生命体征、睡眠和疼痛,提供高精度的术后监测,非常适合活动反馈研究。目的:本研究旨在评估基于可穿戴设备(ePM/ep pod)的活动反馈是否可以减少结直肠癌(CRC)手术30天内的术后并发症。方法:我们进行了一项开放标签、评估盲、随机对照试验,纳入年龄≥18岁计划行结直肠癌手术的患者。患者被随机分为反馈组和对照组。两组术后均根据ERAS指南设定相同的目标活动时间。反馈组每天通过ePM/ep pod装置获得运动时间的实时视觉反馈,对照组不接受反馈。主要观察指标为术后30天的综合并发症指数(CCI)。次要结果包括每日活动时间、术后前3天休息和活动的疼痛数值评定量表评分、住院时间、达到预定活动目标的百分比、术后30天死亡率、第一次排气和排便次数。结果:在2023年2月至2023年9月期间招募了239例患者,其中216例随机化(每组n=108)。对照组(中位CCI 0,范围0-20.90)与活动反馈组(中位CCI 0,范围0-12.20)术后30天CCI无显著差异。估计平均差异为-0.59 (95% CI -3.56至2.38;P= 0.66)。排除低器械依从性患者的敏感性分析没有改变这些发现。两组之间在日常活动时间、住院时间或疼痛评分方面没有显著差异。事后分析显示,术后30天CCI与术后第2天活动量(r=-0.166)和术后第3天活动量(POD3)之间存在显著负相关(r=-0.264)。结论:在ERAS背景下,本研究未发现基于可穿戴设备(ePM/ep pod)反馈的活动刺激可降低结直肠癌手术患者术后30天CCI的证据。而ePM/ep pod能准确记录日活动时长,可能与POD3上的CCI呈负相关。
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引用次数: 0
Assessing Wearable mHealth Adherence in Underserved Adolescents and its Associations With Physical Activity, Sports, and Safety Perceptions: Prospective Cohort Study. 评估服务不足青少年的可穿戴移动健康依从性及其与身体活动、运动和安全感知的关系:前瞻性队列研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-29 DOI: 10.2196/80465
Annabel Nunez-Gaunaurd, Michele Raya

Background: Adolescents from underserved communities, particularly Black and Hispanic youth, engage in lower levels of physical activity (PA), increasing their risk for chronic disease. Conventional interventions often face barriers such as limited access to safe environments. Wearable mobile health technologies offer scalable and context-sensitive solutions; however, predictors of sustained adherence in school-based settings among high-risk populations remain underexplored.

Objective: This study aims to examine the behavioral and contextual predictors of adherence to a consumer-grade wearable PA tracker among underserved high school students.

Methods: In this school-based observational study, 63 students (mean age 14.8, SD 1.17 years) enrolled in physical education received Fitbit devices. Adherence was defined as ≥21 valid days of step count data. Measures included self-reported PA behaviors, neighborhood perceptions, physical fitness (including anthropometrics), and device adherence. Group comparisons were conducted using t tests and chi-square tests. Logistic regression was used to identify predictors of adherence.

Results: Overall, 73% (46/63) of participants met the adherence threshold. Adherent students reported fewer days of moderate-to-vigorous PA (2 vs 4 days/week; P=.004), lower team sports participation (21/46, 46% vs 12/17, 71%; P=.004), and higher perceived neighborhood safety (P=.02). In adjusted models, lower PA frequency, greater perceived safety, and neighborhood walkability significantly predicted adherence (χ² 6=16.23; P=.01, Nagelkerke R²=0.61).

Conclusions: Wearable mobile health technologies show promise for engaging underserved adolescents in PA, particularly those with lower baseline activity and limited access to structured sports. Key predictors of adherence included perceived neighborhood walkability, team sports participation, and prior PA behavior. School-based deployment of wearable devices should emphasize personalized goals and autonomy-supportive strategies to foster sustained engagement and promote PA among high-risk youth.

背景:来自服务不足社区的青少年,特别是黑人和西班牙裔青年,从事较低水平的身体活动(PA),增加了他们患慢性病的风险。常规干预措施往往面临诸如获得安全环境的机会有限等障碍。可穿戴移动医疗技术提供可扩展且对环境敏感的解决方案;然而,高风险人群在学校环境中持续坚持的预测因素仍未得到充分探索。目的:本研究旨在研究缺乏服务的高中生对消费级可穿戴式PA追踪器的依从性的行为和情境预测因素。方法:以学校为基础的观察性研究中,63名体育班学生(平均年龄14.8岁,SD 1.17岁)使用Fitbit设备。依从性定义为≥21有效天的步数数据。测量包括自我报告的PA行为,邻里感知,身体健康(包括人体测量)和设备依从性。采用t检验和卡方检验进行组间比较。使用逻辑回归来确定依从性的预测因子。结果:总体而言,73%(46/63)的参与者达到了依从性阈值。依从性学生报告了较少的中高强度PA天数(2天/周vs 4天/周;P= 0.004),较少的团队运动参与(21/46,46% vs 12/17, 71%; P= 0.004),以及更高的邻里安全感知(P= 0.002)。在调整后的模型中,较低的PA频率、较高的感知安全性和社区步行性显著预测依从性(χ 2 6=16.23; P= 0.01, Nagelkerke R²=0.61)。结论:可穿戴移动医疗技术有望吸引PA服务不足的青少年,特别是那些基线活动量较低和有组织运动机会有限的青少年。依从性的关键预测因素包括感知到的社区步行性、团队运动参与和先前的PA行为。基于学校的可穿戴设备部署应强调个性化目标和自主支持策略,以促进持续参与并促进高风险青少年的PA。
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引用次数: 0
Effects of Telehealth Interventions for People With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials. 远程医疗干预对帕金森病患者的影响:随机对照试验的系统回顾和荟萃分析。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-28 DOI: 10.2196/70994
Minyue Sun, Fuyou Tang, Luo Min, Shiyu Wen, Shuang Wang, Huiping Jiang
<p><strong>Background: </strong>The global integration of telehealth into the management of Parkinson disease (PD) addresses critical gaps in health care access, especially for patients with limited mobility in underserved regions. Despite accelerated adoption during the COVID-19 pandemic, evidence regarding telehealth's multidimensional efficacy remains inconsistent. Previous meta-analyses reported conflicting outcomes for quality of life (QOL), motor symptoms, and neuropsychiatric comorbidities.</p><p><strong>Objective: </strong>This study aimed to quantitatively synthesize the effects of telehealth interventions across six core PD domains: (1) QOL, (2) depression, (3) anxiety, (4) motor symptoms, (5) activities of daily living (ADL), and (6) cognition.</p><p><strong>Methods: </strong>PubMed, Embase, Cochrane Library, Scopus, and Web of Science were systematically searched until June 21, 2024. In adherence to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, English-language randomized controlled trials evaluating telehealth interventions for PD were included. Study quality was assessed using the Cochrane Risk of Bias tool. A dual analytical approach using random-effects models was applied to address heterogeneity. Studies reporting a single effect size were analyzed using the Hartung-Knapp-Sidik-Jonkman correction. Studies with multiple dependent effect sizes were analyzed using a 3-level random-effects meta-analysis with t-distribution inference, accounting for sampling, within-study, and between-study variance. Effect sizes were expressed as standardized mean differences (SMD) with 95% CIs. Heterogeneity was quantified using the τ<sup>2</sup>; prediction intervals were not calculated due to the limited number of studies. Prespecified subgroup analyses examined intervention types (digital vs traditional telehealth) and follow-up durations. Sensitivity analyses and assessments for small-study effects (multilevel Egger tests, funnel plots) were conducted.</p><p><strong>Results: </strong>A total of 15 randomized controlled trials (765 participants) demonstrated significant telehealth benefits: QOL significantly improved on the Medical Outcomes Study 36-Item Short Form Health Survey and Brunnsviken Brief Quality of Life Scale (SMD 0.39, 95% CI 0.06-0.72; P=.03), with marginal improvement on the Parkinson Disease Questionnaire-8 (SMD -0.42, 95% CI -0.88 to 0.03; P=.07). Telephone-based interventions outperformed digital approaches (P=.002). Depression symptoms were significantly reduced (SMD -0.64, 95% CI -0.93 to 0.34; P<.001), particularly with traditional telehealth (P<.001). Anxiety also decreased significantly (SMD -0.64, 95% CI -0.92 to 0.35; P=.003) with negligible heterogeneity (I<sup>2</sup>=0%). Motor symptoms improved (SMD -0.46, 95% CI -0.69 to 0.24; P=.001), and ADL showed substantial impairment reduction (SMD -0.79, 95% CI -1.04 to -0.54; P=.002). Cognition was significantly enhanced (SMD 1.12, 9
背景:全球将远程医疗整合到帕金森病(PD)的管理中,解决了卫生保健可及性方面的关键差距,特别是对服务不足地区行动不便的患者。尽管在2019冠状病毒病大流行期间加快了采用,但关于远程医疗多方面功效的证据仍然不一致。先前的荟萃分析报告了生活质量(QOL)、运动症状和神经精神合并症的相互矛盾的结果。目的:本研究旨在定量综合远程医疗干预对PD六个核心领域的影响:(1)生活质量,(2)抑郁,(3)焦虑,(4)运动症状,(5)日常生活活动(ADL)和(6)认知。方法:系统检索PubMed、Embase、Cochrane Library、Scopus、Web of Science,检索截止至2024年6月21日。遵循PRISMA(系统评价和荟萃分析首选报告项目)指南,纳入了评估PD远程医疗干预的英语随机对照试验。使用Cochrane偏倚风险工具评估研究质量。采用随机效应模型的双重分析方法来解决异质性。报告单一效应量的研究使用hartung - knap - sidik - jonkman校正进行分析。对具有多个依赖效应量的研究,采用具有t分布推断的3水平随机效应荟萃分析,考虑抽样、研究内和研究间方差。效应量以95% ci的标准化平均差异(SMD)表示。异质性用τ2量化;由于研究数量有限,未计算预测区间。预先指定的亚组分析检查了干预类型(数字与传统远程医疗)和随访时间。对小研究效应进行敏感性分析和评估(多水平Egger检验、漏斗图)。结果:共有15项随机对照试验(765名参与者)显示了显著的远程医疗益处:医疗结果研究36项简短健康调查和Brunnsviken简短生活质量量表(SMD - 0.39, 95% CI 0.06-0.72; P= 0.03)的生活质量显著改善,帕金森病问卷-8 (SMD -0.42, 95% CI -0.88 - 0.03; P= 0.07)的生活质量略有改善。基于电话的干预优于数字方法(P= 0.002)。抑郁症状明显减轻(SMD -0.64, 95% CI -0.93 ~ 0.34; P2=0%)。运动症状得到改善(SMD -0.46, 95% CI -0.69至0.24;P= 0.001), ADL表现出显著的损伤减轻(SMD -0.79, 95% CI -1.04至-0.54;P= 0.002)。尽管存在中度异质性(I2=52.3%)和显著的发表偏倚,但认知能力显著增强(SMD 1.12, 95% CI 0.03至2.20;P= 0.045)。结论:远程医疗干预显著增强多个PD域,传统(电话/平板电脑)方法在生活质量和抑郁方面表现出特殊优势。数字干预显示出更有限的效果。这些发现支持远程医疗作为帕金森病的多方面管理工具,尽管认知结果需要进一步调查。试验注册:PROSPERO CRD42024520169;https://www.crd.york.ac.uk/PROSPERO/view/CRD42024520169。
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引用次数: 0
Exploiting Unsupervised Free-Living Data for Cardiorespiratory Fitness Estimation: Systematic Review and Meta-Analysis. 利用无监督的自由生活数据进行心肺健康评估:系统回顾和荟萃分析。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.2196/69996
Alexios Dosis, Aron Berger Syversen, Mikolaj R Kowal, Daniel Grant, Jim Tiernan, David Wong, David G Jayne

Background: Current methods of cardiorespiratory fitness (CRF) assessment may discriminate against frail individuals who are challenged to perform a maximal cardiopulmonary exercise test. CRF estimations from free-living wearable data, captured over extended time periods, may offer a more representative assessment and increase usability in clinical settings.

Objective: This study aimed to review current evidence behind this novel concept and evaluate the performance and quality of models developed to estimate CRF from free-living, unsupervised data.

Methods: Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we systematically searched 4 databases (MEDLINE, Embase, Scopus, and arXiv) for studies reporting the development of models to estimate CRF from continuous free-living wearable data. Studies conducted entirely under controlled laboratory conditions were excluded. Performance metrics were combined in a meta-correlation analysis using a random-effects model and Fisher Z transformation.

Results: Of 1848 papers screened, 18 met the eligibility criteria, with a total of 31,072 participants. The weighted mean age was 46.9 (SD 1.46) years. Multiple computational techniques were used, with 8 studies employing more advanced machine learning models. The meta-correlation analysis revealed a pooled overall estimate of 0.83 with a 95% CI 0.77-0.88. The I2 test indicated high heterogeneity at 97%. Risk of bias assessment found most concerns in the data analysis domain, with studies often lacking clarity around the data handling process.

Conclusions: A promising preliminary agreement between CRF predictions and measured values was noted. However, no definite conclusions can be drawn for clinical implementation due to high heterogeneity among the included studies and lack of external validation. Nonetheless, continuous data streams appear to be a valuable resource that could lead to a step change in how we measure and monitor CRF.

背景:目前的心肺适能(CRF)评估方法可能会对那些接受最大心肺运动测试的体弱个体造成歧视。从自由生活的可穿戴数据中获得的CRF估计,在很长一段时间内,可能会提供更具代表性的评估,并提高临床设置的可用性。目的:本研究旨在回顾这一新概念背后的现有证据,并评估从自由生活、无监督数据中估计CRF的模型的性能和质量。方法:根据PRISMA(首选报告项目用于系统评价和荟萃分析)指南,我们系统地检索了4个数据库(MEDLINE, Embase, Scopus和arXiv),以报告从连续的自由生活可穿戴数据估计CRF的模型开发的研究。完全在受控实验室条件下进行的研究被排除在外。使用随机效应模型和Fisher Z变换,将绩效指标合并到元相关分析中。结果:在筛选的1848篇论文中,18篇符合资格标准,共有31,072名参与者。加权平均年龄46.9岁(SD 1.46)。使用了多种计算技术,其中8项研究采用了更先进的机器学习模型。meta相关分析显示合并总估计值为0.83,95% CI为0.77-0.88。I2检验显示97%的异质性。偏见风险评估是数据分析领域最受关注的问题,研究往往缺乏数据处理过程的清晰度。结论:CRF预测和实测值之间的初步一致是值得注意的。然而,由于纳入的研究具有高度异质性,且缺乏外部验证,尚不能得出临床应用的明确结论。尽管如此,连续的数据流似乎是一种有价值的资源,可以导致我们如何测量和监测CRF的步骤变化。
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JMIR mHealth and uHealth
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