{"title":"Acupuncture for angina post percutaneous coronary intervention: a protocol for systematic review and meta-analysis.","authors":"Xin Zhou, Yanwei Li, Yongjun Yin, Yilan Wang, Wen Xie, Yulan Ren","doi":"10.1136/bmjopen-2024-090964","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Ischaemic heart disease (IHD) is a pathological process characterised by a blockage or non-obstructive accumulation of atherosclerotic plaques in the epicardial arteries. Percutaneous coronary intervention (PCI) is widely used in clinical practice to treat IHD. However, angina post PCI (APPCI) impairs quality of life and portends a worse prognosis. Hence, an effective and safe treatment option remains an urgent need for patients with APPCI. In recent years, there has been an increasing body of clinical trials regarding the use of acupuncture for the prevention and treatment of APPCI, and the results have indicated it might be a promising therapeutic intervention. However, to our knowledge, the potential benefits of acupuncture for the prevention and treatment of APPCI to justify either their recommendation or their clinical role have not been evaluated.</p><p><strong>Methods and analysis: </strong>PubMed, Embase, Cochrane Library, Web of Science Core Collection, Chinese Biomedical Database, Chinese National Knowledge Infrastructure, Wanfang Database and VIP Database will be searched from inception to 8 June 2024 without language restrictions. Two investigators will independently screen studies, extract data, assess the risk of bias from randomised controlled trials (RCTs) and assess the risk of bias. The third reviewer will arbitrate any disagreements. Data synthesis and analysis will be conducted using the RevMan V.5.4 software. Subgroup analyses, sensitivity analysis, meta-regression and bias reporting assessments will be performed if necessary and appropriate. Finally, the quality of evidence from RCTs will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation System tool.</p><p><strong>Ethics and dissemination: </strong>Ethical approval is unnecessary since no private or confidential patient data will be included. The systematic review will be published in peer-reviewed journals.</p><p><strong>Prospero registration number: </strong>CRD42024562116.</p>","PeriodicalId":9158,"journal":{"name":"BMJ Open","volume":"14 12","pages":"e090964"},"PeriodicalIF":2.3000,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667460/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Open","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/bmjopen-2024-090964","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
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Abstract
Introduction: Ischaemic heart disease (IHD) is a pathological process characterised by a blockage or non-obstructive accumulation of atherosclerotic plaques in the epicardial arteries. Percutaneous coronary intervention (PCI) is widely used in clinical practice to treat IHD. However, angina post PCI (APPCI) impairs quality of life and portends a worse prognosis. Hence, an effective and safe treatment option remains an urgent need for patients with APPCI. In recent years, there has been an increasing body of clinical trials regarding the use of acupuncture for the prevention and treatment of APPCI, and the results have indicated it might be a promising therapeutic intervention. However, to our knowledge, the potential benefits of acupuncture for the prevention and treatment of APPCI to justify either their recommendation or their clinical role have not been evaluated.
Methods and analysis: PubMed, Embase, Cochrane Library, Web of Science Core Collection, Chinese Biomedical Database, Chinese National Knowledge Infrastructure, Wanfang Database and VIP Database will be searched from inception to 8 June 2024 without language restrictions. Two investigators will independently screen studies, extract data, assess the risk of bias from randomised controlled trials (RCTs) and assess the risk of bias. The third reviewer will arbitrate any disagreements. Data synthesis and analysis will be conducted using the RevMan V.5.4 software. Subgroup analyses, sensitivity analysis, meta-regression and bias reporting assessments will be performed if necessary and appropriate. Finally, the quality of evidence from RCTs will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation System tool.
Ethics and dissemination: Ethical approval is unnecessary since no private or confidential patient data will be included. The systematic review will be published in peer-reviewed journals.
简介：缺血性心脏病（IHD）是一种以心外膜动脉粥样硬化斑块阻塞或非阻塞性积累为特征的病理过程。经皮冠状动脉介入治疗（PCI）被广泛应用于临床治疗IHD。然而，心绞痛后PCI （APPCI）损害生活质量，预示着较差的预后。因此，APPCI患者迫切需要一种有效且安全的治疗方案。近年来，关于针灸预防和治疗APPCI的临床试验越来越多，结果表明针灸可能是一种有前景的治疗干预措施。然而，据我们所知，针灸预防和治疗APPCI的潜在益处，以证明其推荐或其临床作用的合理性，尚未得到评估。方法与分析：PubMed、Embase、Cochrane图书馆、Web of Science核心馆藏、中国生物医学数据库、中国国家知识基础设施、万方数据库、维普数据库从建库至2024年6月8日检索，无语言限制。两名研究者将独立筛选研究，提取数据，评估随机对照试验（rct）的偏倚风险，并评估偏倚风险。第三位审稿人将对任何分歧进行仲裁。数据综合分析将使用RevMan V.5.4软件进行。如有必要和适当，将进行亚组分析、敏感性分析、元回归和偏倚报告评估。最后，将使用分级建议评估、发展和评估系统工具评估随机对照试验证据的质量。伦理和传播：不需要伦理批准，因为不包括私人或机密的患者数据。系统综述将发表在同行评议的期刊上。普洛斯彼罗注册号：CRD42024562116。
期刊介绍：
BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready.
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