Quercetin nanoparticles as a therapeutic approach: pharmacological actions and potential applications in therapy.

Biotechnologia Pub Date : 2024-12-19 eCollection Date: 2024-01-01 DOI:10.5114/bta.2024.145258
Reham Farouk El-Sayed Baiomy
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Abstract

The utilization of quercetin nanoparticles as a novel therapeutic strategy has garnered significant attention in recent years. These nanoparticles offer a unique approach to enhancing delivery and effectiveness while overcoming the drawbacks of quercetin. By exploiting the advantages of nanotechnology, such as increased stability and improved bioavailability, quercetin nanoparticles hold significant potential for developing innovative treatments across various medical fields. Quercetin nanoparticles have emerged as an indispensable component in numerous pharmaceutical and medicinal formulations. They are recognized for their anticancer, antitumor, anti-inflammatory, and antidiabetic properties, making them valuable in addressing allergic reactions, metabolic disorders, inflammatory disorders, cardiovascular diseases, and arthritis. From a pharmacological perspective, quercetin nanoparticles have demonstrated beneficial effects against Alzheimer's disease, primarily through their inhibitory impact on acetylcholinesterase. Furthermore, these nanoparticles have been scientifically documented to possess antioxidant, anticarcinogenic, hepatoprotective, and cytotoxic activities. This comprehensive review aims to explore the pharmacokinetics and biological activities associated with quercetin nanoparticles. It also highlights their potential as therapeutic agents in treating a wide range of diseases, including Alzheimer's disease, cancer, and neurodegenerative disorders.

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槲皮素纳米颗粒作为一种治疗方法:药理作用和潜在的治疗应用。
近年来,槲皮素纳米颗粒作为一种新的治疗策略得到了广泛的关注。这些纳米颗粒提供了一种独特的方法来增强递送和有效性,同时克服了槲皮素的缺点。槲皮素纳米粒子利用纳米技术的优势,如增加稳定性和提高生物利用度,在开发各种医学领域的创新疗法方面具有巨大潜力。槲皮素纳米颗粒已成为许多药物和药物配方中不可或缺的成分。它们被认为具有抗癌、抗肿瘤、抗炎和抗糖尿病的特性,这使得它们在治疗过敏反应、代谢紊乱、炎症紊乱、心血管疾病和关节炎方面很有价值。从药理学角度来看,槲皮素纳米颗粒主要通过对乙酰胆碱酯酶的抑制作用,证明了对阿尔茨海默病的有益作用。此外,这些纳米颗粒已被科学证明具有抗氧化、抗癌、保护肝脏和细胞毒性活性。本文旨在探讨槲皮素纳米颗粒的药代动力学和生物活性。它还强调了它们作为治疗多种疾病的治疗药物的潜力,包括阿尔茨海默病、癌症和神经退行性疾病。
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