Regular Use of Oral Nonsteroidal Anti-inflammatory Drugs in a Population of Polish Seniors: Findings from the PolSenior2 Cross-Sectional Survey.

IF 3.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY Drugs & Aging Pub Date : 2025-03-01 Epub Date: 2025-01-28 DOI:10.1007/s40266-025-01180-x
Karol Wierzba, Michał Chmielewski, Emilia Błeszyńska-Marunowska, Kacper Jagiełło, Łukasz Wierucki, Tomasz Zdrojewski
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Abstract

Introduction: Older adults represent a growing proportion of the general population. Nonsteroidal anti-inflammatory drugs (NSAIDs) constitute a group of medicines that are both necessary, owing to their anti-inflammatory, analgesic, and cardioprotective abilities, and potentially harmful, owing to their side effects.

Objectives: This study provides a comprehensive analysis of NSAID usage patterns among Polish adults aged 60 years and older. It focused on the regular use (≥ three times per week) of two types of NSAIDs: acetylsalicylic acid (ASA) and non-ASA NSAIDs, examining consumption on the basis of age, sex, educational level, and place of residence.

Methods: Data were collected from the PolSenior2 study, a national cross-sectional survey of 5987 Polish individuals aged 60-106 years, conducted from 2018 to 2019.

Results: The study found that 30.7% [95% confidence interval (CI) 28.8-32.7)]of Polish seniors regularly used NSAIDs, with 26.2% (95% CI 24.5-28.0) regularly using ASA, 6.3% (95% CI 5.3-7.2) regularly using non-ASA NSAIDs, and 1.9% (95% CI 1.4-2.3) reporting regular use of both. An age-related increase in regular NSAID use, including ASA, was observed. Women were more likely than men to use non-ASA NSAIDs regularly, whereas men in the 70-79 age group were more likely to use ASA. A lower level of education was associated with more frequent NSAID use.

Conclusions: The findings have implications for healthcare practitioners and policymakers, emphasizing the need for careful management of NSAID use. The study contributes to a more nuanced understanding of NSAID usage and underscores the necessity for tailored healthcare strategies to ensure safe and effective medication use among older adults.

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波兰老年人口服非甾体类抗炎药的常规使用:来自PolSenior2横断面调查的结果
老年人在总人口中所占的比例越来越大。非甾体类抗炎药(NSAIDs)是一类既因其抗炎、镇痛和心脏保护功能而必不可少,又因其副作用而潜在有害的药物。目的:本研究提供了60岁及以上波兰成年人非甾体抗炎药使用模式的综合分析。该研究主要关注两类非甾体抗炎药的常规使用(每周≥3次):乙酰水杨酸(ASA)和非ASA类非甾体抗炎药,并根据年龄、性别、教育程度和居住地检查其使用情况。方法:数据收集自PolSenior2研究,该研究是一项对5987名60-106岁的波兰人进行的全国性横断面调查,于2018年至2019年进行。结果:研究发现,30.7%[95%置信区间(CI) 28.8-32.7)]的波兰老年人经常使用非甾体抗炎药,其中26.2% (95% CI 24.5-28.0)经常使用ASA, 6.3% (95% CI 5.3-7.2)经常使用非ASA非甾体抗炎药,1.9% (95% CI 1.4-2.3)报告经常使用两者。观察到定期使用非甾体抗炎药(包括ASA)的年龄相关增加。女性比男性更有可能定期使用非ASA类非甾体抗炎药,而70-79岁年龄组的男性更有可能使用ASA类非甾体抗炎药。较低的教育水平与更频繁地使用非甾体抗炎药有关。结论:研究结果对医疗从业者和政策制定者具有启示意义,强调需要仔细管理非甾体抗炎药的使用。该研究有助于对非甾体抗炎药的使用有更细致的了解,并强调了定制医疗保健策略的必要性,以确保老年人安全有效地使用药物。
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来源期刊
Drugs & Aging
Drugs & Aging 医学-老年医学
CiteScore
5.50
自引率
7.10%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Drugs & Aging delivers essential information on the most important aspects of drug therapy to professionals involved in the care of the elderly. The journal addresses in a timely way the major issues relating to drug therapy in older adults including: the management of specific diseases, particularly those associated with aging, age-related physiological changes impacting drug therapy, drug utilization and prescribing in the elderly, polypharmacy and drug interactions.
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