Nyctanthes arbor-tristis Linn.: comprehensive insights into its medicinal, phytochemical and safety profiles.

IF 1.6 3区化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2025-01-28 DOI:10.1080/14786419.2025.2456086

Omkar Tipugade, Jyotiram Sawale, Namdeo Jadhav

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Abstract

Nyctanthes arbor-tristis Linn., commonly known as the 'Tree of Sadness' belongs to Oleaceae family. In Ayurvedic, Siddha, Unani, and Homeopathic therapeutic systems, it has been used to treat various conditions, including ulcers, skin diseases, hair loss, piles, liver diseases, rheumatism, and malarial fevers. Anti-inflammatory, anticonvulsant, anticancer, hepatoprotective, antioxidant, and wound healing actions of extracts from N. arbor-tristis Linn. have been verified by researchers. Alkaloids, tannins, flavonoids, sterols, triterpenes, saponins, and glycosides are the bioactive components found in the plant. This review compiles scientific data from various sources, including Scopus, PubMed, ScienceDirect, and Google Scholar, to provide a comprehensive overview of N. arbor-tristis Linn. It focuses on the plant's pharmacological activities, phytochemical properties, phytoformulation, toxicological aspects, and ethnomedicinal uses, summarising worldwide studies. Future research on N. arbor-tristis Linn. should focus on isolating and characterising bioactive compounds, understanding their mechanisms, conducting toxicological assessments for safety, and exploring synergistic effects with other drugs.

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Nyctanthes arbor-tristis Linn.：对其药用、植物化学和安全性的全面了解。

nycanthes -tristis Linn。，俗称“悲哀树”，属于油棕科。在阿育吠陀、悉达陀、乌纳尼和顺势疗法的治疗系统中，它被用来治疗各种疾病，包括溃疡、皮肤病、脱发、痔疮、肝病、风湿病和疟疾热。黄芪提取物的抗炎、抗惊厥、抗癌、保肝、抗氧化和伤口愈合作用。已被研究人员证实。生物碱、单宁、类黄酮、甾醇、三萜、皂苷和糖苷是植物中发现的生物活性成分。本文综合了来自Scopus、PubMed、ScienceDirect和b谷歌Scholar等不同来源的科学数据，对N. arbort -tristis Linn进行了全面的综述。它侧重于植物的药理活性，植物化学性质，植物配方，毒理学方面，和民族医药用途，总结了世界范围内的研究。木贼的未来研究。应侧重于分离和表征生物活性化合物，了解其机制，进行安全性毒理学评估，并探索与其他药物的协同作用。

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.