Neighbor-aware calibration of segmentation networks with penalty-based constraints

IF 10.7 1区 医学 Q1 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Medical image analysis Pub Date : 2025-02-15 DOI:10.1016/j.media.2025.103501
Balamurali Murugesan , Sukesh Adiga Vasudeva , Bingyuan Liu , Herve Lombaert , Ismail Ben Ayed , Jose Dolz
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Abstract

Ensuring reliable confidence scores from deep neural networks is of paramount significance in critical decision-making systems, particularly in real-world domains such as healthcare. Recent literature on calibrating deep segmentation networks has resulted in substantial progress. Nevertheless, these approaches are strongly inspired by the advancements in classification tasks, and thus their uncertainty is usually modeled by leveraging the information of individual pixels, disregarding the local structure of the object of interest. Indeed, only the recent Spatially Varying Label Smoothing (SVLS) approach considers pixel spatial relationships across classes, by softening the pixel label assignments with a discrete spatial Gaussian kernel. In this work, we first present a constrained optimization perspective of SVLS and demonstrate that it enforces an implicit constraint on soft class proportions of surrounding pixels. Furthermore, our analysis shows that SVLS lacks a mechanism to balance the contribution of the constraint with the primary objective, potentially hindering the optimization process. Based on these observations, we propose NACL (Neighbor Aware CaLibration), a principled and simple solution based on equality constraints on the logit values, which enables to control explicitly both the enforced constraint and the weight of the penalty, offering more flexibility. Comprehensive experiments on a wide variety of well-known segmentation benchmarks demonstrate the superior calibration performance of the proposed approach, without affecting its discriminative power. Furthermore, ablation studies empirically show the model agnostic nature of our approach, which can be used to train a wide span of deep segmentation networks. The code is available at https://github.com/Bala93/MarginLoss
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来源期刊
Medical image analysis
Medical image analysis 工程技术-工程:生物医学
CiteScore
22.10
自引率
6.40%
发文量
309
审稿时长
6.6 months
期刊介绍: Medical Image Analysis serves as a platform for sharing new research findings in the realm of medical and biological image analysis, with a focus on applications of computer vision, virtual reality, and robotics to biomedical imaging challenges. The journal prioritizes the publication of high-quality, original papers contributing to the fundamental science of processing, analyzing, and utilizing medical and biological images. It welcomes approaches utilizing biomedical image datasets across all spatial scales, from molecular/cellular imaging to tissue/organ imaging.
期刊最新文献
Neighbor-aware calibration of segmentation networks with penalty-based constraints From challenges and pitfalls to recommendations and opportunities: Implementing federated learning in healthcare A-Eval: A benchmark for cross-dataset and cross-modality evaluation of abdominal multi-organ segmentation A survey of intracranial aneurysm detection and segmentation Learning robust medical image segmentation from multi-source annotations
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