{"title":"An update on implication of POSS-based nanocomposites in bone tissue engineering: a review.","authors":"Leyla Bagheri, Davoud Jafari-Gharabaghlou, Mohammad-Reza Dashti, Nosratollah Zarghami","doi":"10.1080/09205063.2025.2455234","DOIUrl":null,"url":null,"abstract":"<p><p>The science of Bone tissue engineering (TE) is quickly progressing. Engineering bone usually applications a synthetic extracellular matrix, cells or osteoblasts that can convert to osteoblasts, and adjusting causes that boost adhesion, distinction, and mineralized bone construction of cells. Extremely porous scaffolds perform an important character in cell planting, propagation, and fresh 3D-tissue construction. Reformative medicine and tissue engineering track a multi-disciplinary approach for the novel substances' development and appliance, to the various tissue defects therapy. The presentation of polyhedral oligomeric silsesquioxane (POSS) in the bio-polymeric scaffold has been shown to develop the biotic attributes of the hybrid combinations. This review focuses on the influence of POSS within the Chitosan (CS), Hydroxyapatite (HA), and zeolite matrixes, scaffold drawing, and the advantages and limitations of the materials mentioned for tissue engineering of bone.</p>","PeriodicalId":15195,"journal":{"name":"Journal of Biomaterials Science, Polymer Edition","volume":" ","pages":"1-24"},"PeriodicalIF":3.6000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomaterials Science, Polymer Edition","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/09205063.2025.2455234","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
The science of Bone tissue engineering (TE) is quickly progressing. Engineering bone usually applications a synthetic extracellular matrix, cells or osteoblasts that can convert to osteoblasts, and adjusting causes that boost adhesion, distinction, and mineralized bone construction of cells. Extremely porous scaffolds perform an important character in cell planting, propagation, and fresh 3D-tissue construction. Reformative medicine and tissue engineering track a multi-disciplinary approach for the novel substances' development and appliance, to the various tissue defects therapy. The presentation of polyhedral oligomeric silsesquioxane (POSS) in the bio-polymeric scaffold has been shown to develop the biotic attributes of the hybrid combinations. This review focuses on the influence of POSS within the Chitosan (CS), Hydroxyapatite (HA), and zeolite matrixes, scaffold drawing, and the advantages and limitations of the materials mentioned for tissue engineering of bone.
期刊介绍：
The Journal of Biomaterials Science, Polymer Edition publishes fundamental research on the properties of polymeric biomaterials and the mechanisms of interaction between such biomaterials and living organisms, with special emphasis on the molecular and cellular levels.
The scope of the journal includes polymers for drug delivery, tissue engineering, large molecules in living organisms like DNA, proteins and more. As such, the Journal of Biomaterials Science, Polymer Edition combines biomaterials applications in biomedical, pharmaceutical and biological fields.
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