Bio-nanomaterials: Promising anticancer properties and treatment strategies

Nano TransMed Pub Date : 2025-12-01 Epub Date: 2025-02-21 DOI:10.1016/j.ntm.2025.100076
Elias Emeka Elemike , Innocent Chukwujekwu Onunkwo , Odiri Ughumiakpor , Faith Alawuru , Anthony Mukoro , Peter Ishom , Faith Obarakpor , Ismail Hossain , Andrew E. Aziza
{"title":"Bio-nanomaterials: Promising anticancer properties and treatment strategies","authors":"Elias Emeka Elemike ,&nbsp;Innocent Chukwujekwu Onunkwo ,&nbsp;Odiri Ughumiakpor ,&nbsp;Faith Alawuru ,&nbsp;Anthony Mukoro ,&nbsp;Peter Ishom ,&nbsp;Faith Obarakpor ,&nbsp;Ismail Hossain ,&nbsp;Andrew E. Aziza","doi":"10.1016/j.ntm.2025.100076","DOIUrl":null,"url":null,"abstract":"<div><div>One of the most difficult diseases to treat in people is cancer, and its mortality rate has recently increased significantly. Nanoparticles are used in the rapidly developing field of cancer nanomedicine to diagnose and as well treat cancer. The often-systemic effects with conventional therapy have now been minimized by the ability of nanoparticles to release normally considered insoluble medicines to tumor locations both far and near. Due to their strong qualities and effects, which include biocompatibility, biosafety, biodegradability, synergistic and autologous therapeutic effects, biologically-based nanomaterials have drawn great interests with regards to cancer therapy. It has been extensively discussed and discovered that nucleic acid, polysaccharides, polyphenol or phenolics, proteins (also peptide), cell and subcellular fractions, as well as lipid are bioactive substances. The utilization of these biologically-active materials in nano-formulation is promising toward efficient treatment of cancer through by different oncological therapeutic strategies. As a result of their structural characterizations, adaptable characteristics, anti-tumor processes, and biological performances, these bioactive compounds have been specifically used as examples of the functions of composite nanosystems.</div></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"4 ","pages":"Article 100076"},"PeriodicalIF":0.0000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano TransMed","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S279067602500007X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/21 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

One of the most difficult diseases to treat in people is cancer, and its mortality rate has recently increased significantly. Nanoparticles are used in the rapidly developing field of cancer nanomedicine to diagnose and as well treat cancer. The often-systemic effects with conventional therapy have now been minimized by the ability of nanoparticles to release normally considered insoluble medicines to tumor locations both far and near. Due to their strong qualities and effects, which include biocompatibility, biosafety, biodegradability, synergistic and autologous therapeutic effects, biologically-based nanomaterials have drawn great interests with regards to cancer therapy. It has been extensively discussed and discovered that nucleic acid, polysaccharides, polyphenol or phenolics, proteins (also peptide), cell and subcellular fractions, as well as lipid are bioactive substances. The utilization of these biologically-active materials in nano-formulation is promising toward efficient treatment of cancer through by different oncological therapeutic strategies. As a result of their structural characterizations, adaptable characteristics, anti-tumor processes, and biological performances, these bioactive compounds have been specifically used as examples of the functions of composite nanosystems.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
生物纳米材料:抗癌特性和治疗策略
癌症是人类最难治疗的疾病之一,其死亡率最近显著上升。纳米粒子被用于快速发展的癌症纳米医学领域,用于诊断和治疗癌症。由于纳米颗粒能够将通常被认为不溶性的药物释放到肿瘤的远近部位,传统疗法的全身效应现在已经降到最低。由于生物基纳米材料具有生物相容性、生物安全性、生物可降解性、协同性和自体治疗效应等优良特性和效果,在癌症治疗方面引起了人们极大的兴趣。核酸、多糖、多酚或酚类物质、蛋白质(也包括肽)、细胞和亚细胞组分以及脂质都是生物活性物质,已被广泛讨论和发现。这些生物活性物质在纳米制剂中的应用有望通过不同的肿瘤治疗策略来有效地治疗癌症。由于其结构特征、适应性特征、抗肿瘤过程和生物学性能,这些生物活性化合物已被专门用作复合纳米系统功能的例子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Unveiling the frontiers of self-assembled chinese herbal medicines nanodrugs in cancer therapy: A comprehensive bibliometric analysis and insights into emerging vesicle-based strategies A mini-review on the multimodal applications of engineered magnetic nanoparticles in diagnosis and therapy Next-generation injectable hydrogels: Advanced crosslinking strategies, multi-stimuli responsiveness, and translational advances for precision regenerative medicine SNEDDS delivery of black sticky rice extract: Hepatoprotective and antioxidant potential Curcumin poly D-L lactide nanoparticles demonstrate superior antiplasmodial Efficacy and multi-target binding compared with dihydroartemisinin: Integrative in vivo and in silico analyses
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1