Tomoki Sakata MD, PhD , Yuki Nakamura MD, PhD , Keshava Rajagopal MD, PhD , Vakhtang Tchantchaleishvili MD , Konstadinos A. Plestis MD , John W. Entwistle III MD, PhD , Joseph E. Bavaria MD , Rakesh M. Suri MD, DPhil
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引用次数: 0
Abstract
Background
Temporary mechanical circulatory support (tMCS) may be necessary to treat low cardiac output syndrome after mitral valve surgery (MVS) for chronic severe mitral regurgitation (MR). However, prevalence and predictors remain undetermined.
Methods
This single-center retrospective cohort study included 443 patients who underwent primary MVS for degenerative, ischemic, or functional MR between January 2013 and June 2023. Patients requiring tMCS intraoperatively or postoperatively were compared with patients who did not require tMCS. Multivariable logistic regression identified independent risk factors for tMCS requirement.
Results
tMCS was required in 12 of 443 patients (2.7%), with degenerative (2.1%), functional (1.8%), and ischemic (8.3%) MR. Independent risk factors for tMCS requirement were preoperative left ventricular ejection fraction <50% (odds ratio, 4.94; P = .01) and mitral valve replacement (odds ratio, 5.85; P = .005). MR type was not independently influential. The 30-day mortality was 41.7% (5 of 12) in the tMCS group vs 3.5% (15 of 431) in the non-tMCS group (P < .0001).
Conclusions
Requirements for tMCS after MVS for MR are infrequent, but tMCS is associated with high mortality. Low preoperative left ventricular ejection fraction and mitral valve replacement are independent risk factors, thus suggesting that careful surgical planning and meticulous postoperative monitoring are warranted in high-risk cases.