Influence of meteorological and environmental factors on pediatric urinary tract infections: insights from a 6-year retrospective study in Central China.
{"title":"Influence of meteorological and environmental factors on pediatric urinary tract infections: insights from a 6-year retrospective study in Central China.","authors":"Changzhen Li, Feng Tang, Lei Xi, Xiaomei Wang","doi":"10.3389/fpubh.2025.1512403","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the association between meteorological factors and common uropathogens in children with urinary tract infections (UTIs) and assesses the potential influence of weather conditions on pediatric UTIs.</p><p><strong>Study design: </strong>Analyze the demographic and uropathogen characteristics from children with culture-proven UTIs and its correlation with meteorological factors.</p><p><strong>Methods: </strong>2,411 data from infants and children with UTIs in a children's hospital from 2016 to 2021 were retrospectively analyzed. A correlation analysis was conducted to investigate the relationship between the monthly detection number of uropathogens and meteorological factors.</p><p><strong>Results: </strong>Multiple linear stepwise regression analyses showed a positive correlation between monthly average temperature, precipitation volume, sunshine hours, monthly total number of uropathogens, and the number of <i>E. coli</i> and <i>E. faecalis</i>. <i>E. faecium</i> was predominant in <12-month-old children, while <i>E. coli</i> was dominant in the 3-18-year age category. <i>E. faecium</i> showed a higher prevalence in girls, while <i>E. faecalis</i> was more prevalent in boys. <i>E. coli</i> exhibited resistance rates of >40% to second-or third-generation cephalosporins in multiple age groups. <i>E. faecium</i> showed high resistance rates to tetracyclines, fluoroquinolones, erythromycin, ampicillin, and penicillin, while <i>K. pneumoniae</i> displayed higher sensitivity to cephalosporin-sulbactam and amikacin, but higher resistance rates to cefazolin and ceftazidime.</p><p><strong>Conclusion: </strong>This study reveals the association between meteorological factors and uropathogens in children with UTIs, as well as the distribution, age-related characteristics, gender differences and antibiotic resistance profiles of pathogenic bacteria. These findings inform the development of targeted strategies for UTI prevention and treatment based on uropathogenic characteristics and meteorological conditions.</p>","PeriodicalId":12548,"journal":{"name":"Frontiers in Public Health","volume":"13 ","pages":"1512403"},"PeriodicalIF":3.4000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864906/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fpubh.2025.1512403","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: To investigate the association between meteorological factors and common uropathogens in children with urinary tract infections (UTIs) and assesses the potential influence of weather conditions on pediatric UTIs.
Study design: Analyze the demographic and uropathogen characteristics from children with culture-proven UTIs and its correlation with meteorological factors.
Methods: 2,411 data from infants and children with UTIs in a children's hospital from 2016 to 2021 were retrospectively analyzed. A correlation analysis was conducted to investigate the relationship between the monthly detection number of uropathogens and meteorological factors.
Results: Multiple linear stepwise regression analyses showed a positive correlation between monthly average temperature, precipitation volume, sunshine hours, monthly total number of uropathogens, and the number of E. coli and E. faecalis. E. faecium was predominant in <12-month-old children, while E. coli was dominant in the 3-18-year age category. E. faecium showed a higher prevalence in girls, while E. faecalis was more prevalent in boys. E. coli exhibited resistance rates of >40% to second-or third-generation cephalosporins in multiple age groups. E. faecium showed high resistance rates to tetracyclines, fluoroquinolones, erythromycin, ampicillin, and penicillin, while K. pneumoniae displayed higher sensitivity to cephalosporin-sulbactam and amikacin, but higher resistance rates to cefazolin and ceftazidime.
Conclusion: This study reveals the association between meteorological factors and uropathogens in children with UTIs, as well as the distribution, age-related characteristics, gender differences and antibiotic resistance profiles of pathogenic bacteria. These findings inform the development of targeted strategies for UTI prevention and treatment based on uropathogenic characteristics and meteorological conditions.
期刊介绍：
Frontiers in Public Health is a multidisciplinary open-access journal which publishes rigorously peer-reviewed research and is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians, policy makers and the public worldwide. The journal aims at overcoming current fragmentation in research and publication, promoting consistency in pursuing relevant scientific themes, and supporting finding dissemination and translation into practice.
Frontiers in Public Health is organized into Specialty Sections that cover different areas of research in the field. Please refer to the author guidelines for details on article types and the submission process.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
