An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning.

IF 2.6 3区 医学 Q2 OPHTHALMOLOGY Translational Vision Science & Technology Pub Date : 2025-03-03 DOI:10.1167/tvst.14.3.4
Bo Zheng, Chen Wang, Maotao Zhang, Shaojun Zhu, Maonian Wu, Tao Wu, Weihua Yang, Lu Chen
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Abstract

Purpose: To develop an intelligent grading model for myopic maculopathy based on a long-tail learning framework, using the improved loss function LTBSoftmax. The model addresses the long-tail distribution problem in myopic maculopathy data to provide preliminary grading, aiming to improve grading capability and efficiency.

Methods: This study includes a data set of 7529 color fundus photographs. Experienced ophthalmologists meticulously annotated the ground truth. A new intelligent grading model for myopic maculopathy was constructed using the improved loss function LTBSoftmax, which predicts lesions by locally enhancing feature extraction with ND Block. Standard grading metrics were selected to evaluate the LTBSoftmax model.

Results: The improved model demonstrated excellent performance in diagnosing four types of myopic maculopathy, achieving a κ coefficient of 88.89%. Furthermore, the model's size is 18.7 MB, which is relatively smaller compared to traditional models, indicating that the model not only achieves a high level of agreement with expert diagnoses but is also more efficient in terms of both storage and computational resources. These metrics further validate the model's well-conceived design and superiority in practical applications.

Conclusions: The intelligent grading system, using long-tailed learning strategies, effectively improves the classification of myopic maculopathy, offering a practical grading tool for clinicians, particularly in areas with limited resources.

Translational relevance: This model translates long-tail learning research into a practical grading tool for myopic maculopathy. It addresses data imbalance with the improved LTBSoftmax loss function, achieving high accuracy and efficiency. By enhancing feature extraction with ND Block, it provides reliable grading support for clinicians, especially in resource-limited settings.

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来源期刊
Translational Vision Science & Technology
Translational Vision Science & Technology Engineering-Biomedical Engineering
CiteScore
5.70
自引率
3.30%
发文量
346
审稿时长
25 weeks
期刊介绍: Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO. The journal covers a broad spectrum of work, including but not limited to: Applications of stem cell technology for regenerative medicine, Development of new animal models of human diseases, Tissue bioengineering, Chemical engineering to improve virus-based gene delivery, Nanotechnology for drug delivery, Design and synthesis of artificial extracellular matrices, Development of a true microsurgical operating environment, Refining data analysis algorithms to improve in vivo imaging technology, Results of Phase 1 clinical trials, Reverse translational ("bedside to bench") research. TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.
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