Yang Zou, Qinrong He, Yudong Song, Xiangyu Yang, Xinjian Shi, Shengyan Yin, Song Liang, Zhenning Liu, Hang Sun
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引用次数: 0
Abstract
Postcharging antibacterials have shown good application prospects in combating bacterial infections through electrical interaction. Herein, manganese oxide nanosheets in situ grown on carbon fibers (CM) are designed to perform the integration of mechanical intervention and postcharging therapy for efficient bacterial killing. This electrode disrupts bacterial membranes via sharp-edged microstructures. After charging at a low voltage in an ultrashort time, the charged CM affects the extracellular electron transfer (EET) of bacteria during the discharge process to kill the bacteria. Due to the dual-antibacterial mode, after charging at −1 V (vs saturated calomel electrode, SCE) for only 50.4 ± 3 s, the bacteria lethality rates of the CM against Escherichia coli and Staphylococcus aureus within 0.5 h both exceed 98%. Our developed ultrafast negatively charged CM exhibits high antibacterial activity and low cytotoxicity to fibroblast cells, providing a non-antibiotic approach to combat bacterial infection.
期刊介绍：
Nano Letters serves as a dynamic platform for promptly disseminating original results in fundamental, applied, and emerging research across all facets of nanoscience and nanotechnology. A pivotal criterion for inclusion within Nano Letters is the convergence of at least two different areas or disciplines, ensuring a rich interdisciplinary scope. The journal is dedicated to fostering exploration in diverse areas, including:
- Experimental and theoretical findings on physical, chemical, and biological phenomena at the nanoscale
- Synthesis, characterization, and processing of organic, inorganic, polymer, and hybrid nanomaterials through physical, chemical, and biological methodologies
- Modeling and simulation of synthetic, assembly, and interaction processes
- Realization of integrated nanostructures and nano-engineered devices exhibiting advanced performance
- Applications of nanoscale materials in living and environmental systems
Nano Letters is committed to advancing and showcasing groundbreaking research that intersects various domains, fostering innovation and collaboration in the ever-evolving field of nanoscience and nanotechnology.
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