LW-CTrans: A lightweight hybrid network of CNN and Transformer for 3D medical image segmentation

IF 10.7 1区 医学 Q1 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Medical image analysis Pub Date : 2025-03-17 DOI:10.1016/j.media.2025.103545
Hulin Kuang , Yahui Wang , Xianzhen Tan , Jialin Yang , Jiarui Sun , Jin Liu , Wu Qiu , Jingyang Zhang , Jiulou Zhang , Chunfeng Yang , Jianxin Wang , Yang Chen
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Abstract

Recent models based on convolutional neural network (CNN) and Transformer have achieved the promising performance for 3D medical image segmentation. However, these methods cannot segment small targets well even when equipping large parameters. Therefore, We design a novel lightweight hybrid network that combines the strengths of CNN and Transformers (LW-CTrans) and can boost the global and local representation capability at different stages. Specifically, we first design a dynamic stem that can accommodate images of various resolutions. In the first stage of the hybrid encoder, to capture local features with fewer parameters, we propose a multi-path convolution (MPConv) block. In the middle stages of the hybrid encoder, to learn global and local features meantime, we propose a multi-view pooling based Transformer (MVPFormer) which projects the 3D feature map onto three 2D subspaces to deal with small objects, and use the MPConv block for enhancing local representation learning. In the final stage, to mostly capture global features, only the proposed MVPFormer is used. Finally, to reduce the parameters of the decoder, we propose a multi-stage feature fusion module. Extensive experiments on 3 public datasets for three tasks: stroke lesion segmentation, pancreas cancer segmentation and brain tumor segmentation, show that the proposed LW-CTrans achieves Dices of 62.35±19.51%, 64.69±20.58% and 83.75±15.77% on the 3 datasets, respectively, outperforming 16 state-of-the-art methods, and the numbers of parameters (2.08M, 2.14M and 2.21M on 3 datasets, respectively) are smaller than the non-lightweight 3D methods and close to the lightweight methods. Besides, LW-CTrans also achieves the best performance for small lesion segmentation.
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来源期刊
Medical image analysis
Medical image analysis 工程技术-工程:生物医学
CiteScore
22.10
自引率
6.40%
发文量
309
审稿时长
6.6 months
期刊介绍: Medical Image Analysis serves as a platform for sharing new research findings in the realm of medical and biological image analysis, with a focus on applications of computer vision, virtual reality, and robotics to biomedical imaging challenges. The journal prioritizes the publication of high-quality, original papers contributing to the fundamental science of processing, analyzing, and utilizing medical and biological images. It welcomes approaches utilizing biomedical image datasets across all spatial scales, from molecular/cellular imaging to tissue/organ imaging.
期刊最新文献
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