Assessing Etoposide and Cyclophosphamide Contamination and Current Cleaning Practices in Patient Bathrooms.

IF 1.3 4区医学 Q3 NURSING Clinical journal of oncology nursing Pub Date : 2025-03-14 DOI:10.1188/25.CJON.E52-E59

AnnMarie L Walton, Margaret A Bush, Anthony D Sung, Melissa A Powell, Haesu J Jin, Susan G Silva, Ivan Spasojevic

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引用次数: 0

Abstract

Background: Antineoplastic drug (AD) exposure presents severe risks to healthcare workers. Previous studies have demonstrated that patient bathrooms are highly contaminated and have led to concern for excreta as a source of environmental contamination with ADs.

Objectives: This study assessed AD contamination and current cleaning practices to remove AD surface contamination in patient bathrooms.

Methods: Three surfaces in the bathrooms of patients who had received etoposide and/or cyclophosphamide were sampled and analyzed for contamination at three time points. Liquid chromatography-tandem mass spectrometry was used for analysis. Interviews and observations of daily and discharge cleaning were conducted to understand cleaning practices.

Findings: A significant reduction in etoposide contamination on toilets and floors was observed following discharge cleaning; however, no significant reduction was observed on walls for either AD or on floors for cyclophosphamide.

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来源期刊

Clinical journal of oncology nursing ONCOLOGY-NURSING

CiteScore

1.70

自引率

9.10%

发文量

127

审稿时长

6-12 weeks

期刊介绍： The Clinical Journal of Oncology Nursing (CJON) is an official publication of the Oncology Nursing Society (ONS) and is directed to the practicing nurse specializing in the care of patients with an actual or potential diagnosis of cancer. CJON is a vehicle to promote the mission of ONS, which is to advance excellence in oncology nursing and quality cancer care. The CJON mission is twofold: to provide practical information necessary to care for patients and their families across the cancer continuum and to develop publication skills in oncology nurses.