{"title":"Few-Shot Medical Image Segmentation with High-Confidence Prior Mask.","authors":"Ziming Cheng, Jianqin Zhao, Jingjing Deng, Haofeng Zhang","doi":"10.1109/JBHI.2025.3552428","DOIUrl":null,"url":null,"abstract":"<p><p>Labeling large amounts of medical data is travailing, leading to the blooming of few-shot medical image segmentation, which aims to segment the foreground of a query image given a labeled support set. Almost all current models adopt the cosine distance to measure the similarity between prototypes and query features. However, the limitation of the cosine distance is exacerbated by intra-class differences and inter-class imbalances in medical image scenarios, where angle-only evaluation can induce misclassification to under- and over-segmentation. Motivated by this, we propose a High-Confidence Prior Mask-guided Network (HCPMNet), comprising a High-Confidence Mask Generator (HCPMG), a Target Region Mining (TRM) module, and a Prototype-Oriented Expansion Match (POEM) module. Our HCPMNet offers key advantages: 1) HCPMG is the first to combinatively evaluate angle and magnitude similarity, generating high-confidence priori masks that accurately and completely localize target regions. 2) TRM mines and aggregates target class information under the guidance of priori masks. 3) POEM, based on both similarity metrics, correctly matches prototypes with query features. Extensive experiments on three general medical datasets show that our HCPMNet achieves a new SoTA with great superiority. The code is available at: https://github.com/zmcheng9/HCPMNet.</p>","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7000,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Journal of Biomedical and Health Informatics","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1109/JBHI.2025.3552428","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Labeling large amounts of medical data is travailing, leading to the blooming of few-shot medical image segmentation, which aims to segment the foreground of a query image given a labeled support set. Almost all current models adopt the cosine distance to measure the similarity between prototypes and query features. However, the limitation of the cosine distance is exacerbated by intra-class differences and inter-class imbalances in medical image scenarios, where angle-only evaluation can induce misclassification to under- and over-segmentation. Motivated by this, we propose a High-Confidence Prior Mask-guided Network (HCPMNet), comprising a High-Confidence Mask Generator (HCPMG), a Target Region Mining (TRM) module, and a Prototype-Oriented Expansion Match (POEM) module. Our HCPMNet offers key advantages: 1) HCPMG is the first to combinatively evaluate angle and magnitude similarity, generating high-confidence priori masks that accurately and completely localize target regions. 2) TRM mines and aggregates target class information under the guidance of priori masks. 3) POEM, based on both similarity metrics, correctly matches prototypes with query features. Extensive experiments on three general medical datasets show that our HCPMNet achieves a new SoTA with great superiority. The code is available at: https://github.com/zmcheng9/HCPMNet.
期刊介绍:
IEEE Journal of Biomedical and Health Informatics publishes original papers presenting recent advances where information and communication technologies intersect with health, healthcare, life sciences, and biomedicine. Topics include acquisition, transmission, storage, retrieval, management, and analysis of biomedical and health information. The journal covers applications of information technologies in healthcare, patient monitoring, preventive care, early disease diagnosis, therapy discovery, and personalized treatment protocols. It explores electronic medical and health records, clinical information systems, decision support systems, medical and biological imaging informatics, wearable systems, body area/sensor networks, and more. Integration-related topics like interoperability, evidence-based medicine, and secure patient data are also addressed.