Advanced Intervention Effects of Pulsed and Steady Transcranial Photobiomodulation on Sleep, Mood, and EEG Signal Regulation.

Journal of biophotonics Pub Date : 2025-03-18 DOI:10.1002/jbio.70004

Xuran Zhang, Xiaojing Miao, Hui Jiang, Yi Ren, Longfei Huo, Muqing Liu, Houbo Chen

{"title":"Advanced Intervention Effects of Pulsed and Steady Transcranial Photobiomodulation on Sleep, Mood, and EEG Signal Regulation.","authors":"Xuran Zhang, Xiaojing Miao, Hui Jiang, Yi Ren, Longfei Huo, Muqing Liu, Houbo Chen","doi":"10.1002/jbio.70004","DOIUrl":null,"url":null,"abstract":"Background: Transcranial photobiomodulation (tPBM) enhances cognitive and emotional states. We compared continuous-wave (CW) and pulsed-wave (PW) tPBM effects on 24 healthy males.Method: Participants received 630 nm tPBM at 95 mW/cm2 for 10 min: Sham, CW, or PW (500 Hz). Outcomes were assessed using the Karolinska Sleepiness Scale (KSS) (for measuring sleepiness), State-Trait Anxiety Inventory (STAI) (for assessing anxiety), Visual Analog Scale (VAS) (for measuring stress), and Beck Depression Inventory-II (BDI-II) (for evaluating depressive symptoms), and 32-channel EEG at baseline, treatment, and rest phases.Results: Paired t-tests showed PW tPBM significantly improved sleepiness, anxiety, stress, and depression scores post-intervention (p < 0.05). ANOVA analyses indicated PW tPBM increased Alpha and Gamma band EEG power versus baseline (p < 0.05).Conclusion: PW tPBM may improve cognitive and emotional outcomes and modulate brain activity, offering therapeutic insights.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e70004"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/jbio.70004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Transcranial photobiomodulation (tPBM) enhances cognitive and emotional states. We compared continuous-wave (CW) and pulsed-wave (PW) tPBM effects on 24 healthy males.

Method: Participants received 630 nm tPBM at 95 mW/cm² for 10 min: Sham, CW, or PW (500 Hz). Outcomes were assessed using the Karolinska Sleepiness Scale (KSS) (for measuring sleepiness), State-Trait Anxiety Inventory (STAI) (for assessing anxiety), Visual Analog Scale (VAS) (for measuring stress), and Beck Depression Inventory-II (BDI-II) (for evaluating depressive symptoms), and 32-channel EEG at baseline, treatment, and rest phases.

Results: Paired t-tests showed PW tPBM significantly improved sleepiness, anxiety, stress, and depression scores post-intervention (p < 0.05). ANOVA analyses indicated PW tPBM increased Alpha and Gamma band EEG power versus baseline (p < 0.05).

Conclusion: PW tPBM may improve cognitive and emotional outcomes and modulate brain activity, offering therapeutic insights.

查看原文