[The expression of nuclear factor kappa B in cancer cells of human adenocarcinoma].

Abstract

Objective: Nuclear factor kappa B is very important in cis-activation which regulates the expression of many genes. This study inquired into the mechanism of cancer cell metastasis.

Methods: Immunohistochemical method was used for studying the expression of nuclear factor kappa B in cancer cells of human metastasized rectum adenocarcinoma.

Results: Expressed nuclear factor kappa Bp65 was found in the cancer cells of peritumoral tissues and metastasized lymph nodes. The reaction product was located in the cytoplasm and cytonucleus.

Conclusion: The findings of this study suggest a strong correlation between the expression of nuclear factor kappa B in cancer cells and the metastasis of cancer.