{"title":"Toxicity studies of α-pinene administered by inhalation to F344/N rats and B6C3F1/N mice.","authors":"","doi":"10.22427/NTP-TOX-81","DOIUrl":null,"url":null,"abstract":"<p><p>α-Pinene is the main component in turpentine and is used as a fragrance and flavoring ingredient. Due to widespread exposure potential and a lack of available toxicity data, male and female F344/N rats and B6C3F1/N mice were exposed to α-pinene (96% pure) by inhalation for 2 weeks or 3 months. Genetic toxicology studies were conducted in Salmonella typhimurium, Escherichia coli, and mouse peripheral blood erythrocytes. (Abstract Abridged).</p>","PeriodicalId":23116,"journal":{"name":"Toxicity report series","volume":" 81","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039871/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicity report series","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22427/NTP-TOX-81","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
α-Pinene is the main component in turpentine and is used as a fragrance and flavoring ingredient. Due to widespread exposure potential and a lack of available toxicity data, male and female F344/N rats and B6C3F1/N mice were exposed to α-pinene (96% pure) by inhalation for 2 weeks or 3 months. Genetic toxicology studies were conducted in Salmonella typhimurium, Escherichia coli, and mouse peripheral blood erythrocytes. (Abstract Abridged).