Janne J Näppi, Rie Tachibana, Daniele Regge, Hiroyuki Yoshida
{"title":"Information-Preserving Pseudo-Enhancement Correction for Non-Cathartic Low-Dose Dual-Energy CT Colonography.","authors":"Janne J Näppi, Rie Tachibana, Daniele Regge, Hiroyuki Yoshida","doi":"10.1007/978-3-319-13692-9_15","DOIUrl":null,"url":null,"abstract":"<p><p>In CT colonography (CTC), orally administered positive-contrast fecal-tagging agents can cause artificial elevation of the observed radiodensity of adjacent soft tissue. Such pseudo-enhancement makes it challenging to differentiate polyps and folds reliably from tagged materials, and it is also present in dual-energy CTC (DE-CTC). We developed a method that corrects for pseudo-enhancement on DE-CTC images without distorting the dual-energy information contained in the data. A pilot study was performed to evaluate the effect of the method visually and quantitatively by use of clinical non-cathartic low-dose DE-CTC data from 10 patients including 13 polyps covered partially or completely by iodine-based fecal tagging. The results indicate that the proposed method can be used to reduce the pseudo-enhancement distortion of DE-CTC images without losing material-specific dual-energy information. The method has potential application in improving the accuracy of automated image-processing applications, such as computer-aided detection and virtual bowel cleansing in CTC.</p>","PeriodicalId":91045,"journal":{"name":"Abdominal imaging : computational and clinical applications : 6th International Workshop, ABDI 2014, held in conjunction with MICCAI 2014, Cambridge, MA, USA, September 14, 2014. ABDI (Workshop) (6th : 2014 : Cambridge, Mass.)","volume":"8676 ","pages":"159-168"},"PeriodicalIF":0.0000,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-319-13692-9_15","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Abdominal imaging : computational and clinical applications : 6th International Workshop, ABDI 2014, held in conjunction with MICCAI 2014, Cambridge, MA, USA, September 14, 2014. ABDI (Workshop) (6th : 2014 : Cambridge, Mass.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-3-319-13692-9_15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
In CT colonography (CTC), orally administered positive-contrast fecal-tagging agents can cause artificial elevation of the observed radiodensity of adjacent soft tissue. Such pseudo-enhancement makes it challenging to differentiate polyps and folds reliably from tagged materials, and it is also present in dual-energy CTC (DE-CTC). We developed a method that corrects for pseudo-enhancement on DE-CTC images without distorting the dual-energy information contained in the data. A pilot study was performed to evaluate the effect of the method visually and quantitatively by use of clinical non-cathartic low-dose DE-CTC data from 10 patients including 13 polyps covered partially or completely by iodine-based fecal tagging. The results indicate that the proposed method can be used to reduce the pseudo-enhancement distortion of DE-CTC images without losing material-specific dual-energy information. The method has potential application in improving the accuracy of automated image-processing applications, such as computer-aided detection and virtual bowel cleansing in CTC.