Multidimensional Approaches for A Case of Severe Adult Obsessive - Compulsive Disorder.

Zhongyong Shi, Xinchun Mei, Yingbo Zhu, Yu Shuai, Yupeng Chen, Yujie Wu, Yuan Shen
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Abstract

Obsessive-compulsive disorder (OCD) is a chronic, distressing and substantially impairing neuropsychiatric disorder, characterized by obsessions or compulsions. The current case describes a 44-year-old adult female diagnosed with OCD. The patient had an incomplete response to several SSRIs alone during her past treatment, and led a poor-quality life for at least three years. Current multidimensional approaches, including combined cognitive behavioral therapy (CBT) and the Selective Serotonin Reuptake Inhibitor (SSRI, Sertraline) with a small dose of antipsychotics (Aripiprazole) for augmentation, as well as familial support and resources from the internet were provided for the patient for six months. Standardized assessments with Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) every two months indicated significant reductions in obsessive and compulsive symptoms, with significant improvements in her social functioning and quality of life. A case such as this one provides preliminary support to multidimensional approaches for OCD treatment in order to achieve an optimal response, though further rigorous clinical trials are needed to provide more evidence.

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成人重度强迫症的多维方法研究。
强迫症(OCD)是一种慢性、痛苦和严重损害的神经精神疾病,以强迫或强迫为特征。目前的病例描述了一名44岁的成年女性,被诊断患有强迫症。在过去的治疗中,患者对几种单独的SSRIs没有完全的反应,并且至少有三年的生活质量很差。目前的多维方法,包括联合认知行为疗法(CBT)和选择性血清素再摄取抑制剂(SSRI,舍曲林)加小剂量抗精神病药物(阿立哌唑),以及家庭支持和来自互联网的资源,为患者提供了6个月。每两个月进行一次耶鲁-布朗强迫症量表(Y-BOCS)的标准化评估表明,强迫和强迫症状显著减轻,社交功能和生活质量显著改善。虽然需要进一步严格的临床试验来提供更多的证据,但像这样的一个案例为强迫症治疗的多维方法提供了初步支持,以达到最佳效果。
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