A Study of The Clinical Effect and Dropout Rate of Drugs Combined with Group Integrated Psychotherapy on Elderly Patients with Depression.

上海精神医学 Pub Date : 2018-02-25 DOI:10.11919/j.issn.1002-0829.217051

Bo Liu, Youguo Tan, Duanfang Cai, Yudiao Liang, Ruini He, Chengwen Liu, Yong Zhou, Cuihua Teng

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引用次数: 2

Abstract

Background: Relevant studies have shown that group cognitive behavioral therapy is effective in treating patients with depressive disorder, but the dropout rate is high. The present study is aimed to explore the patterns of integrated group psychotherapy.

Aims: This study investigated the clinical effects of integrated group psychotherapy for elderly patients with senile depression.

Methods: One hundred elderly patients with senile depression were divided into the experiment group (n=50) and the control group (n=50) randomly. The experiment group was given regular pharmacological treatments combined with integrated group psychotherapy, while the control group was given regular pharmacological treatments combined with integrated group cognitive behavioral therapy. These two groups were assessed with the Hamilton Depression Scale (HAMD-24) and Geriatric Depression Scale (GDS-15) before the study and at two weeks, four weeks and eight weeks after the treatments.

Results: According to the comparisons within these two groups, it was found that the HAMD and GDS total scores before treatments were all significantly higher than those after treatments (F=102.50, p=0.001; F=55.94, p<0.001). We found that the HAMD total scores after four weeks and eight weeks were significantly different between the two groups (F=3.82, p=0.021). The differences between two groups' GDS total scores after two weeks, four weeks and eight weeks were also significantly different (F=4.49, p=0.009). Seven cases dropped out in the experiment group, while sixteen cases dropped out in the control group. The difference of dropout rates was statistically significant (x² =4.57, p=0.032).

Conclusion: Medication treatments combined with the group integrated psychotherapy significantly improve the clinical effect for elderly patients with senile depression. The compliance is improved and the dropout rate declines.

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药物联合团体综合心理治疗老年抑郁症的临床疗效及辍学率研究。

背景:相关研究表明，群体认知行为疗法治疗抑郁症患者有效，但中途退出率高。本研究旨在探讨整合团体心理治疗的模式。目的:探讨综合团体心理治疗对老年抑郁症患者的临床疗效。方法:将100例老年抑郁症患者随机分为实验组(n=50)和对照组(n=50)。实验组给予常规药物治疗结合团体综合心理治疗，对照组给予常规药物治疗结合团体综合认知行为治疗。在研究前和治疗后2周、4周和8周分别用汉密尔顿抑郁量表(HAMD-24)和老年抑郁量表(GDS-15)对两组患者进行评估。结果:两组间比较，治疗前HAMD、GDS总分均显著高于治疗后(F=102.50, p=0.001;F=55.94, pF=3.82, p=0.021)。两组患者治疗后2周、4周、8周的GDS总分差异也有统计学意义(F=4.49, p=0.009)。实验组退出7例，对照组退出16例。两组辍学率差异有统计学意义(x2 =4.57, p=0.032)。结论:药物治疗结合团体综合心理治疗可显著提高老年抑郁症患者的临床疗效。依从性提高，辍学率下降。

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上海精神医学

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