Identifying cancer risks using spectral subset feature selection based on multi-layer perception neural network for premature treatment.

Abstract

Recently, human beings have been affected mainly by dreadful cancer diseases. Predicting cancer risk levels is a major challenge in biomedical research for feature selection and classification at the margins. To resolve this problem, we propose a Subset Clustering-Based Feature Selection using a Multi-Layer Perception Neural Network (SCFS-MLPNN). Initially, pre-processing is carried out with Intensive Mutual Disease Influence Rate (IMDIR) to identify the relational features. In addition, the Successive Disease Pattern Stimulus Rate (SDPSR) is carried out to create relative feature patterns. Based on the patterns, the features are selected and grouped into clustering. Inter-Class Sub-Space Clustering (ICSSC) is applied to split the features by class labels depending on the marginal rate. From the class labels, marginal features are obtained using spectral subset feature selection (SSFS). The selected features are then trained in a Multi-Layer Perception Neural Network (MLPNN) classifier to classify the patient features by risk. Its contribution is to exploit subset features to improve classification accuracy by clustering relational features. The proposed classifier yields higher classification accuracy than previous methods and observes cancer detection for early detection. Therefore, the proposed method achieved a risk analysis accuracy of 91.8% and an F-measure of 91.3% for early detection, which is recommended for early diagnosis.