Transcranial Magnetic Stimulation: New Sapience into How Brain Stimulation Palliates Symptoms of PTSD

S. Khare
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Abstract

Posttraumatic stress disorder (PTSD) is a chronic, often debilitating psychological state disorder that may develop after a traumatic life event. Most patients get over the initial symptoms naturally, but those that experience persistent symptoms require standard treatment approaches such as 1: 1 psychotherapy, psychotropic medications, or both whichever have relevance. However, there are secondary hindrances such as drug safety and drug tolerability associated with these psychotropic medications, that interdict an appropriate course of treatment. The upshot of those events is that it creates a breach in our potential to properly manage PTSD in a significant number of patients, leaving them endangered to surfacing complications like employment-related incapacities, suicidal ideations, co-morbid medical disorders, and illicit drug abuse. Thus, there is a need for more worthwhile, tolerable, and long-standing approaches. Transcranial magnetic stimulation may be a safe and non-invasive treatment technique used to treat various psychiatric and neurological disorders. This neuromodulation technique involves stimulation of specific deep brain regions by the assembly of high and low-intensity magnetic fields thus filling the therapeutic void. This text mainly focuses on the results of controlled and pragmatic trials for efficacy, safety, and tolerability of patients affected by PTSD. The alternative treatment for PTSD currently is psychotherapy and antidepressant medications.Despite receiving these alternatives, there are about 50% of patients who continue to experience major symptoms..That is, the reason why TMS came out as another suitable option. Atleast 5 directories such as MEDLINE, CINAHL, Psych INFO, SCOPUS and EMBASE were probed to pinpoint pragmatic studies and randomized controlled trials that were designed for the treatment of PTSD with TMS. A total of 28 studies were found worthy for this review, out of which 5 are mentioned in this article. Although, so far it looks propitious in spite of the manifoldness as far as its outcomes and its clinical importance are concerned. Hence, still researches involving stimulation constraints are to be conducted in the near future.
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经颅磁刺激:脑刺激如何缓解创伤后应激障碍症状的新发现
创伤后应激障碍(PTSD)是一种慢性的、经常使人衰弱的心理状态障碍,可能在创伤生活事件后发展。大多数患者会自然克服最初的症状,但那些经历持续症状的患者需要标准的治疗方法,如1:1心理治疗、精神药物或两者兼有。然而,与这些精神药物相关的药物安全性和药物耐受性等次要障碍阻碍了适当的疗程。这些事件的结果是,它破坏了我们在大量患者中正确管理创伤后应激障碍的潜力,使他们面临出现并发症的危险,如与工作相关的丧失能力、自杀意念、共病医疗障碍和非法药物滥用。因此,有必要采取更有价值、可容忍和长期的办法。经颅磁刺激可能是一种安全、无创的治疗技术,用于治疗各种精神和神经疾病。这种神经调控技术包括通过高强度和低强度磁场的组合来刺激特定的脑深部区域,从而填补治疗空白。本文主要关注创伤后应激障碍患者的疗效、安全性和耐受性的对照和实用试验结果。目前PTSD的替代治疗方法是心理治疗和抗抑郁药物。尽管接受了这些替代方案,但仍有约50%的患者继续出现重大症状。。也就是说,TMS之所以成为另一个合适的选择。对MEDLINE、CINAHL、Psych INFO、SCOPUS和EMBASE等至少5个目录进行了探索,以确定应用TMS治疗创伤后应激障碍的实用研究和随机对照试验。共有28项研究值得进行本综述,其中5项在本文中提到。尽管就其结果和临床重要性而言,它看起来是有利的,尽管它有很多优点。因此,在不久的将来仍将进行涉及刺激约束的研究。
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