Thyroidectomy as Treatment of Choice for Differentiated Thyroid Cancer

IF 1.6 Q4 ONCOLOGY International Journal of Surgical Oncology Pub Date : 2019-10-13 DOI:10.1155/2019/2715260
D. Giuffrida, R. Giuffrida, I. Puliafito, V. Vella, L. Memeo, C. Puglisi, C. Regalbuto, G. Pellegriti, S. Forte, A. Belfiore
{"title":"Thyroidectomy as Treatment of Choice for Differentiated Thyroid Cancer","authors":"D. Giuffrida, R. Giuffrida, I. Puliafito, V. Vella, L. Memeo, C. Puglisi, C. Regalbuto, G. Pellegriti, S. Forte, A. Belfiore","doi":"10.1155/2019/2715260","DOIUrl":null,"url":null,"abstract":"Background Despite a large amount of data, the optimal surgical management of differentiated thyroid cancer remains controversial. Current guidelines recommend total thyroidectomy if primary thyroid cancer is >4 cm, while for tumors that are between 1 and 4 cm in size, either a bilateral or a unilateral thyroidectomy may be appropriate as surgical treatment. In general, total thyroidectomy would seem to be preferable because subtotal resection can be correlated with a higher risk of local recurrences and cervical lymph node metastases; on the other hand, total thyroidectomy is associated with more complications. Methods This is a retrospective study conducted on 359 patients with differentiated thyroid cancer, subjected to total thyroidectomy. Our aim was to correlate clinical and pathological features (extrathyroid tumor growth, bilaterality, nodal and distant metastasis) with patient (gender and age) and tumor (size and histotype) characteristics. Moreover, we recorded postoperative complications, including hypoparathyroidism and laryngeal nerve damage. Results In our study, we found a high occurrence of pathological features indicating cancer aggressiveness (bilaterality, nodal metastases, and extrathyroid invasion). On the other hand, total thyroidectomy was associated with relatively low postsurgical complication rates. Conclusions Our data support the view that total thyroidectomy remains the first choice for the routine treatment of differentiated thyroid cancer.","PeriodicalId":45960,"journal":{"name":"International Journal of Surgical Oncology","volume":"2019 1","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2019-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2715260","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Surgical Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2019/2715260","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 5

Abstract

Background Despite a large amount of data, the optimal surgical management of differentiated thyroid cancer remains controversial. Current guidelines recommend total thyroidectomy if primary thyroid cancer is >4 cm, while for tumors that are between 1 and 4 cm in size, either a bilateral or a unilateral thyroidectomy may be appropriate as surgical treatment. In general, total thyroidectomy would seem to be preferable because subtotal resection can be correlated with a higher risk of local recurrences and cervical lymph node metastases; on the other hand, total thyroidectomy is associated with more complications. Methods This is a retrospective study conducted on 359 patients with differentiated thyroid cancer, subjected to total thyroidectomy. Our aim was to correlate clinical and pathological features (extrathyroid tumor growth, bilaterality, nodal and distant metastasis) with patient (gender and age) and tumor (size and histotype) characteristics. Moreover, we recorded postoperative complications, including hypoparathyroidism and laryngeal nerve damage. Results In our study, we found a high occurrence of pathological features indicating cancer aggressiveness (bilaterality, nodal metastases, and extrathyroid invasion). On the other hand, total thyroidectomy was associated with relatively low postsurgical complication rates. Conclusions Our data support the view that total thyroidectomy remains the first choice for the routine treatment of differentiated thyroid cancer.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
甲状腺切除术作为分化型甲状腺癌的治疗选择
背景尽管有大量的数据,分化型甲状腺癌的最佳手术治疗仍然存在争议。目前的指南建议,如果原发性甲状腺癌的大小为4cm,则应进行全甲状腺切除术,而对于大小在1 - 4cm之间的肿瘤,则可采用双侧或单侧甲状腺切除术作为手术治疗。总的来说,甲状腺全切除术似乎更可取,因为次全切除术可能与局部复发和颈部淋巴结转移的高风险相关;另一方面,全甲状腺切除术的并发症较多。方法对359例行甲状腺全切除术的分化型甲状腺癌患者进行回顾性研究。我们的目的是将临床和病理特征(甲状腺外肿瘤生长、双侧、淋巴结和远处转移)与患者(性别和年龄)和肿瘤(大小和组织型)特征联系起来。此外,我们还记录了术后并发症,包括甲状旁腺功能减退和喉神经损伤。结果在我们的研究中,我们发现高发生率的病理特征表明癌症的侵袭性(双侧,淋巴结转移和甲状腺外浸润)。另一方面,甲状腺全切除术的术后并发症发生率相对较低。结论甲状腺全切除术仍是分化型甲状腺癌常规治疗的首选。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
期刊最新文献
Translation and Cross-Cultural Adaptation of the Toronto Extremity Salvage Score (TESS) for Latin American Spanish-Speaking Patients With Limb Sarcoma: Latin American Spanish TESS Adaptation. The Sublingual Gland Flap for Oral Reconstruction: Insights From a Single Institutional Experience. Novel Index Combining Pan-Immune-Inflammatory Index and Hemoglobin Levels (PIV/Hb) Predicts Trismus Rates Efficiently after Chemoradiotherapy in Locally Advanced Nasopharyngeal Cancer. Risk Factors for Early Postoperative Morbidity and Mortality following Extremity Metastatic Pathologic or Impending Fracture Fixation. Differentiated Thyroid Carcinoma Long-Term Prognostic Factors.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1