Therapeutic effect of intravenous thrombolysis combined with drug therapy on mild ischemic stroke

Abstract

Objective To explore the effect of dual antiplatelet combined with calf serum deproteinized injection in the treatment of mild ischemic stroke after intravenous thrombolysis. Methods From October 2017 to December 2018, 82 patients with mild ischemic stroke who were diagnosed in the People's Hospital of Ruian were selected.The patients were divided into control group (41 cases) and observation group (41 cases) according to random number table method.The control group was treated with aspirin after intravenous thrombolysis.On this basis, the observation group was treated with dual antiplatelet combined with calf serum deproteinized injection.The course of treatment was 3 months in both two groups.The total effective rate, the changes of hemorheological indicators, the improvement of neurological deficit, the ability of daily living and the ability of returning to society were compared between the two groups before and after treatment.The complications and prognosis were recorded. Results The total effective rate of the observation group was 95.12% (39/41), which was higher than 78.05% (32/41) of the control group (χ2=5.145, P 0.05). Conclusion After intravenous thrombolytic therapy for patients with mild ischemic stroke, dual antiplatelet therapy combined with calf serum deproteinized injection can improve the neurological function, life ability and hemorheological indicators of patients, with good prognosis, it is safe and effective. Key words: Stroke; Thrombolytic therapy; Aspirin; Platelet aggregation inhibitors; Calf serum deproteinized injection; Drug therapy, combination; Hemorheology; Prognosis