Blood Hypothermic Storage and Erythrocyte Cryopreservation in Dogs

G. Zhegunov, O. Denysova, Galina Zhegunova
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Abstract

This review presents the analysis of reported data on the current methods for blood hypothermic storage and erythrocyte cryopreservation in dogs. The relevance of designing and improving the techniques for canine erythrocyte cryopreservation, cryobanking, as well as the application of cryopreserved blood components for transfusion were substantiated. The features of canine blood hypothermic storage and specific use of cryoprotectants with various modes of their action were considered. The advantages of applying DMSO and combined cryopreservatives during low temperature storage of canine erythrocytes were specified.
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狗的血液低温储存和红细胞低温保存
本文对目前犬血液低温保存和红细胞冷冻保存方法的报道数据进行了分析。证实了设计和改进犬红细胞冷冻保存技术、冷冻库技术以及冷冻保存血液成分在输血中的应用的相关性。考虑了犬血液低温储存的特点以及冷冻保护剂的特殊用途及其各种作用模式。阐述了二甲基亚砜和联合冷冻保存剂在犬红细胞低温保存中的优点。
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来源期刊
Problems of Cryobiology and Cryomedicine
Problems of Cryobiology and Cryomedicine Medicine-Medicine (miscellaneous)
CiteScore
0.60
自引率
0.00%
发文量
9
期刊介绍: The Journal publishes the reviews and original papers on cryobiological and cryomedical research, in particular the elucidation of mechanisms of injuries occurring in biological objects and caused by the influence of low and ultra low temperatures; natural resistance of biologicals to cold and their recovery post effect; the development of effective methods of cryoprotection and technology of storage of biological resources under hypothermic and ultra low temperatures, application of hypothermia, cryotherapy and cryopreserved biologicals for treating various pathologies; cell and tissue based therapies and other issues of low-temperature biology and medicine, as well as development of devices and equipment for low temperature biology and medicine. The journal covers all topics related to low temperature biology, medicine and engineering. These include but are not limited to: low temperature storage of biologicals (human, animal or plant cells, tissues, and organs), including preparation for storage, thawing/warming, cell and tissue culturing etc. response of biologicals to low temperature; cold adaptation of animals and plants; utilisation of low temperature in medicine; experimental and clinical transplantation, cell and tissue based therapies; developing of cryobiological and cryomedical devices; organisation and functioning of low temperature banks etc.
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