Severe uncontrolled allergic eosinophilic asthma – looking for the best therapeutic option

I. Kupryś-Lipińska, P. Kuna
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Abstract

In this article the authors analyze in detail the clinical role of immunoglobulins E and eosinophils in the etiology and pathogenesis of asthma, and their impact on the course of asthma. They discuss problems related to the treatment of severe bronchial asthma and new therapeutic options. They recall the positions of experts on the criteria for qualifying for biological therapies and discuss the order of drug use, especially in the group of patients presenting simultaneously the phenotype of allergic and eosinophilic asthma.
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严重不受控制的过敏性嗜酸性哮喘-寻找最佳治疗方案
本文详细分析了免疫球蛋白E和嗜酸性粒细胞在哮喘病因病机中的临床作用及其对哮喘病程的影响。他们讨论了与治疗严重支气管哮喘和新的治疗方案有关的问题。他们回顾了专家对生物治疗资格标准的立场,并讨论了药物使用顺序,特别是在同时出现过敏性和嗜酸性哮喘表型的患者组中。
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来源期刊
自引率
50.00%
发文量
18
期刊介绍: Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.
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