Oral anti-COVID-19 drugs that were recently evaluated by FDA or EMA: a review

Dorota Lorenz, R. Pawliczak
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引用次数: 2

Abstract

Y COVID-19 is an infectious disease that is caused by coronavirus SARS-CoV-2. As the time passed it became clear that, aside from the vaccines, other efficient methods of fighting the disease are urgently needed. Among the whole list of medicines used to treat COVID-19, those which are administered orally have a great advantage. The aim of this paper is to present the current knowledge about the recently investigated oral medications for COVID-19. The authors present molnupiravir (Lagevrio), baricitinib (Olumiant) and ritonavir + PF-07321332 (Paxlovid). All of these drugs have been registered recently or are waiting for authorization by EMA or FDA. During the study, the authors learned that huge progress was made, nevertheless, more studies are needed, especially in the field of side effects and drug-drug interactions of the considered substances.
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最近通过FDA或EMA评估的口服抗covid -19药物:综述
新冠肺炎是一种由冠状病毒SARS-CoV-2引起的传染病。随着时间的推移,很明显,除了疫苗之外,迫切需要其他有效的方法来对抗这种疾病。在用于治疗COVID-19的整个药物清单中,口服药物具有很大优势。本文的目的是介绍最近研究的COVID-19口服药物的最新知识。作者推荐莫努匹拉韦(Lagevrio)、巴比替尼(Olumiant)和利托那韦+ PF-07321332 (Paxlovid)。所有这些药物最近都已注册或正在等待EMA或FDA的授权。在研究过程中,作者了解到已经取得了巨大的进展,但还需要进行更多的研究,特别是在所考虑的物质的副作用和药物-药物相互作用领域。
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来源期刊
自引率
50.00%
发文量
18
期刊介绍: Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.
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