Rate of major complications is higher in laparoscopic than abdominal hysterectomy but quality of life improves with both procedures

Lee A Learman M.D., Ph.D., F.A.C.O.G. (Commentary Author)
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引用次数: 4

Abstract

Question

Is the risk of major complications greater following laparoscopic hysterectomy compared with abdominal and vaginal hysterectomy for non-malignant conditions?

Study design

Two parallel, multi-centre randomised trials.

Main results

More major complications were experienced with laparoscopic hysterectomy compared with abdominal hysterectomy (11.1% vs 6.2%; mean difference 4.9%, 95% CI 0.9% to 9.1%, number needed to harm 20). There was no significant difference in complication rates between laparoscopic and vaginal hysterectomy groups (complication rate 9.5% for both groups).

Pain scores were higher following abdominal hysterectomy compared with laparoscopic hysterectomy (mean difference 0.4, 95% CI 0.09 to 0.7). There was no detectable difference in the vaginal trial. Quality of life at 12 months improved with all interventions.

Authors’ conclusions

Major complications were more common following laparoscopic hysterectomy compared with abdominal hysterectomy. The vaginal trial was inconclusive.

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腹腔镜子宫切除术的主要并发症发生率高于腹部子宫切除术,但两种手术的生活质量都有所改善
问题对于非恶性疾病,腹腔镜子宫切除术后发生主要并发症的风险是否比腹部和阴道子宫切除术更大?研究设计两项平行、多中心的随机试验。主要结果腹腔镜子宫切除术与腹式子宫切除术相比,并发症发生率更高(11.1%vs 6.2%;平均差异4.9%,95%CI 0.9%-9.1%,需要伤害20个)。腹腔镜和阴道子宫切除术组的并发症发生率没有显著差异(两组的并发症率均为9.5%)。与腹腔镜子宫切除术相比,腹式子宫切除术后的疼痛评分更高(平均差异0.4,95%CI 0.09-0.7)。阴道试验中没有可检测的差异。通过所有干预措施,12个月时的生活质量有所改善。作者的结论腹腔镜子宫切除术后主要并发症比腹部子宫切除术更常见。阴道试验没有结论。
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