Consuming less than 4 alcoholic drinks per week does not increase risk of pre-term delivery

Heather L. Paladine MD (Commentary Author)
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Abstract

Question

Is there an association between the amount and type of alcohol consumed during pregnancy and the risk of pre-term delivery?

Study design

Prospective cohort study.

Main results

Of 40, 892 pregnant women, 1880 (4.6%) had pre-term delivery. The adjusted relative risk of pre-term delivery in all women consuming 2–3.5 drinks per week was lower than in non-drinkers (RR 0.80, 95% CI 0.68 to 0.96). The risk was not statistically significant when only nulliparous women were included. Other levels of alcohol consumption were not associated with a statistically significant increased or decreased risk of pre-term delivery compared with non-drinkers except for nulliparous women who drank ⩾7 drinks per week (RR 2.91, 95% CI 1.29 to 6.55). There was no relationship between risk of pre-term delivery and the preferred type of alcohol (wine, beer, spirits or mixed).

Authors’ conclusions

Consumption of 7 or more drinks per week was associated with an increased risk of pre-term delivery in woman having their first child. Pre-term delivery was not affected by type of alcohol intake.

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每周饮酒少于4杯不会增加早产的风险
问题怀孕期间饮酒的数量和类型与早产风险之间是否存在关联?研究设计前瞻性队列研究。主要结果在40892名孕妇中,1880人(4.6%)早产。每周饮酒2-3.5杯的所有女性的调整后早产相对风险均低于不饮酒的女性(RR 0.80,95%CI 0.68-0.96)。当仅包括未产妇时,风险无统计学意义。与不喝酒的人相比,除了每周喝7杯酒的未产妇外,其他饮酒水平与早产风险的增加或降低没有统计学意义(RR 2.91,95%CI 1.29至6.55)。早产风险与首选的酒精类型(葡萄酒、啤酒、烈酒或混合酒)之间没有关系结论每周饮用7杯或7杯以上的饮料与有第一个孩子的妇女早产风险增加有关。早产不受酒精摄入类型的影响。
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