Comparative screening of anti-sickling reported and traditional herbs found in Chhattisgarh

Abstract

Sickle cell anaemia (SCA) has been recognized as a serious genetic disorder throughout the World. This genetic abnormality arises at the sixth position of β-chain of haemoglobin, where amino acid valine is replaced by glutamic acid. SCA has already been announced as an endemic in Chhattisgarh state. Chhattisgarh is well known for its enriched source of herbal plants. People use herbal system of medicine for the management of sickle cell anaemia. Folk healers have sound knowledge of herbal and food plants and they have been practicing such nutraceuticals on sickle anaemic patients for many years. Present review is all about reported and traditional herb. Moreover, we have performed phytochemical screening of some traditional herbs which are being used by the healer’s. on the basis of screening data we have compared the bio-constituents of both reported and traditional herbs. Thus, the present work has encompassed review as well as comparative data. This paper will be beneficial for the new budding researchers for the further assessment of such plants for their anti-sickling activity. Keywords: Sickle cell anaemia, Endemic, Traditional healers, Nutraceuticals, Phytochemical screening.