To study the incidence of pre-hospital antibiotic therapy among critically ill patients admitted in rural tertiary care hospital

Guntupalli Suma Geetika, S. Natekar, A. Shetti
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Abstract

There is considerate amount of stress which lies in the application of antibiotics in critically ill patients. A study on pre-hospital antibiotic administration in such patients would provide crucial data and go a long way in determining and understanding trends in antibiotic prescribing, to identify where necessary steps to be taken to improve prescribing are most needed and to measure progress. Materials and Methods:  After ethical committee approval, we have conducted an observational crosssectional study for four months. We collected the data from patient or the relatives regarding prehospital antibiotic therapy on admission. Results: A total of 137 patients got admitted in the Medical intensive care unit (MICU) during the study period. Out of them, 91.24% of patients got admitted directly in MICU and 8.75% were referred from different hospitals. Those who received antibiotics prior to the admission were 2.18% and 93.43% of patients had not received antibiotics; the other patients who were not sure of antibiotic consumption were 4.37%. Among those 2.18% of patients who received, it was observed the most commonly utilized first antibiotic in our study was amoxicillin clavulanate potassium 66.66%. In all the patients that received more than one antibiotic, Metronidazole was the second antibiotic that was administered via intravenous route. Conclusion: Amoxicillin clavulanate potassium was the most commonly and metronidazole was the second most antibiotic prescribed in prehospital admission. Proper guidelines should be initiated for the starting of the antibiotic therapies in India for general practitioners. Keywords: Antibiotics, Incidence, Prehospital, Critically ill.
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目的了解农村三级医院危重病人院前抗生素治疗情况
在危重病人中应用抗生素的压力是相当大的。对这类患者院前抗生素使用情况的研究将提供关键数据,并有助于确定和了解抗生素处方的趋势,确定在哪些地方最需要采取必要步骤改进处方,并衡量进展情况。材料和方法:经伦理委员会批准,我们进行了为期4个月的观察性横断面研究。我们收集了患者或其亲属关于入院前抗生素治疗的资料。结果:研究期间共有137例患者入住内科重症监护病房(MICU)。其中,91.24%的患者直接入住icu, 8.75%的患者转诊至其他医院。入院前接受抗生素治疗的占2.18%,未接受抗生素治疗的占93.43%;不确定抗生素使用情况的占4.37%。在接受治疗的2.18%的患者中,我们的研究中最常用的第一抗生素是阿莫西林克拉维酸钾,占66.66%。在所有接受一种以上抗生素治疗的患者中,甲硝唑是静脉注射的第二种抗生素。结论:院前住院用药以克拉维酸阿莫西林钾最常见,甲硝唑次之。应该为印度全科医生开始抗生素治疗制定适当的指导方针。关键词:抗生素,发病率,院前,危重症
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