Tuberculous Meningitis with dengue – A rare case

A. Shetti, P. Ahiwale
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Abstract

A 23-year male patient came to Rural Tertiary Care Hospital with complaints of fever, difficulty in talking, disorientation and neck stiffness and was diagnosed with Dengue. When Dengue antibody testing was done, IgM was positive while IgG and NS1 being negative. We report an evaluation of an IgM seropositive case for dengue who showed neurological manifestation whose MRI Brain suggested Meningitis. CSF examination suggested Tuberculous Meningitis in the course of the infection. The patient responded to medications during hospitalisation, was discharged in a haemodynamically stable condition and was advised to continue with antitubercular treatment and tapering dose of oral steroids. Hence one should not avoid considering a Cerebrospinal fluid examination especially of patients belonging to Dengue endemic areas. Keywords: CSF examination, Dengue, Meningitis, Tuberculosis.
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结核性脑膜炎合并登革热-罕见病例
一名23岁男性患者以发热、说话困难、定向障碍和颈部僵硬为主诉来到农村三级保健医院,诊断为登革热。登革抗体检测IgM阳性,IgG和NS1阴性。我们报告了一个IgM血清阳性的登革热病例的评估,该病例显示神经学表现,其MRI脑提示脑膜炎。脑脊液检查提示感染过程中为结核性脑膜炎。患者在住院期间对药物有反应,出院时血流动力学稳定,并建议继续进行抗结核治疗和逐渐减少口服类固醇剂量。因此,不应避免考虑进行脑脊液检查,特别是对属于登革热流行地区的患者。关键词:脑脊液检查,登革热,脑膜炎,肺结核。
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