{"title":"Photosensitizers and photochemistry (Conference Presentation)","authors":"L. Arnaut","doi":"10.1117/12.2536227","DOIUrl":null,"url":null,"abstract":"We will discuss product target profiles that photosensitizers for PDT should met to satisfy the requirements of clinical PDT. Next, we will review the spectroscopy and photochemistry of the main families of photosensitizers with an impact in clinical PDT. We will critically examine the factors that made such photosensitizers appealing for PDT and their shortcomings. Finally, an overview of opportunities ahead will be presented.\n \nTopics addressed\n – The phototherapeutic window\n – Electronic spectroscopy of porphyrin derivatives, phthalocyanines and BODIPYs\n – Photochemistry and ROS\n – Factors contributing to the performance of PDT sensitizers","PeriodicalId":6365,"journal":{"name":"17th International Photodynamic Association World Congress","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"17th International Photodynamic Association World Congress","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.2536227","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We will discuss product target profiles that photosensitizers for PDT should met to satisfy the requirements of clinical PDT. Next, we will review the spectroscopy and photochemistry of the main families of photosensitizers with an impact in clinical PDT. We will critically examine the factors that made such photosensitizers appealing for PDT and their shortcomings. Finally, an overview of opportunities ahead will be presented.
Topics addressed
– The phototherapeutic window
– Electronic spectroscopy of porphyrin derivatives, phthalocyanines and BODIPYs
– Photochemistry and ROS
– Factors contributing to the performance of PDT sensitizers
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