Seroprevalence of Cytomegalovirus among Schizophrenic Patients in Khartoum State

A. Malik, Fatima Hamid, Mohammed Sir Alkhatim Mohammed Ahmed Fateh Elrahman Abshr, Mazin Mustafa Alkhair Abozaid, Mohammed Fadelmoula Sabahelkhair Idris, M. Hamad, Omar Abdalla Osman Ahmed, Safa Abu Eella Merghani Mohammed, Salma Yaha Algack Alnasry, Yomo Dino Yor Lual
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Abstract

Background: Human Cytomegalovirus (HCMV) is a microbe capable to establish lifetime tenacious infections. Schizophrenia is a mental malady described by atypical social behavior and failure to comprehend what is actual. Objectives: To recognize the seroprevalence of cytomegalovirus between schizophrenic patients in Khartoum state. Methods: Hospital based, descriptive cross sectional study, eighty schizophrenic patients participated in the study. Results: The CMV seropositive detected in 31 patients with the percentage 38.75%. 18 of seropositive patients were males with the percentage 58.06%, while 13 of them were female with the percentage 41.9%. Conclusion: Our study revealed that Males are more affected with both schizophrenia and cytomegalovirus. Further studies are required with large sample size and other laboratory diagnostic methods to detect CMV such as Polymerase chain reaction technique.
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喀土穆州精神分裂症患者巨细胞病毒血清阳性率分析
背景:人类巨细胞病毒(HCMV)是一种能够建立终生顽固感染的微生物。精神分裂症是一种精神疾病,表现为不典型的社会行为和无法理解现实。目的:了解喀土穆地区精神分裂症患者巨细胞病毒的血清阳性率。方法:以医院为基础,采用描述性横断面研究方法,对80例精神分裂症患者进行研究。结果:CMV血清阳性31例,检出率38.75%。血清阳性患者中男性18例,占58.06%,女性13例,占41.9%。结论:我们的研究表明,男性在精神分裂症和巨细胞病毒两种疾病中患病率更高。进一步的研究需要大样本量和其他实验室诊断方法来检测巨细胞病毒,如聚合酶链反应技术。
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