GC-MS analysis of anti-mark ointment formulation for skin burns

A. Shahanaz, G. Subiksha, M. Yuha, A. GowriShankarB
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Abstract

Wounds generated from burns are fatal and cause marks that last for a long period of time. The formulation of anti marks cream especially for burns would provide hope for a better way of treating scars. The aim of this study is to prepare an ointment using hair ash and oil along with aloevera followed by the characterization of compounds by using Gas Chromatography and Mass Spectroscopy (GC-MS).The natural compounds used could possibly reduce any side effects on the skin. The GC-MS analysis of the ointment revealed the presence of 30 bioactive compounds. The predominant bioactive compounds were especially fatty acids such as hexadecanoic acid, tetradecanoic acid, dodecanoic acid and octadecanoic acid. The antibacterial, antioxidant, anti-inflammatory, antifungal properties of these bioactive compounds could be effectively used in the treatment of scars.
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皮肤烧伤抗痕软膏配方的GC-MS分析
烧伤造成的伤口是致命的,会留下很长一段时间的痕迹。专门用于烧伤的防痕膏的配方为更好地治疗疤痕提供了希望。本研究的目的是制备一种以芦荟为原料的灰分油软膏,并采用气相色谱-质谱联用技术对其成分进行表征。使用的天然化合物可能会减少对皮肤的任何副作用。气相色谱-质谱分析显示该软膏含有30种生物活性化合物。主要的生物活性成分以脂肪酸为主,如十六烷酸、十四烷酸、十二烷酸和十八烷酸。这些生物活性化合物具有抗菌、抗氧化、抗炎、抗真菌等特性,可有效地用于疤痕的治疗。
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