Proliferative Verrucous Leukoplakia of the Gingiva, Report of two Cases with Malignant Transformation

N. Ghanee, Selene Saraf, M. N. Kilo, Kristina Waggoner
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Abstract

J Clin Anat Pathol 2017 | Vol 3: 101 Abstract Gingival Squamous Cell Carcinoma (SCC) may present with varied clinical and histological appearances. Proliferative verrucous Leukoplakia (PVL) is a high risk non-homogenous leukoplakia. PVL has a high probability of recurrence and has shown a high rate of malignant transformation to either squamous cell carcinoma or verrucous carcinoma. This paper discusses two cases of gingival PVL with malignant transformation. Both patients were female, ages 62 and 70 who were seen at the oral pathology clinic in Kaiser. The initial biopsy results on both cases were suggestive of PVL. Close observation and repeated follow up visits showed recurrent lesions and subsequently early detection of SCC.
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牙龈增生性疣状白斑2例并恶性转化
牙龈鳞状细胞癌(SCC)可能表现出多种临床和组织学表现。增殖性疣状白斑(PVL)是一种高风险的非均匀性白斑。PVL有很高的复发率,并有很高的恶性转化为鳞状细胞癌或疣状癌的几率。本文讨论了2例牙龈PVL伴恶性转化的病例。两名患者均为女性,年龄分别为62岁和70岁,均在凯撒口腔病理诊所就诊。两例患者的初步活检结果均提示PVL。密切观察和反复随访发现复发病变,随后早期发现鳞状细胞癌。
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