Evaluation of Liver Fibrosis in Cirrhotic Patients: Comparison between Elastoso- nography and Fibroscan

S. Roma, C. Pace, A. Amico, I. Lenci, S. Francioso, C. Chiaramonte, F. Chegai, A. Orlacchio
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Abstract

To date, there are still no clear data on the validity of Shear Waves Elastography (SWE) techniques in assessing liver fibrosis. Our study aimed to compare the stiffness liver values obtained with SWE techniques with Transient Elastography (TE) and to identify the threshold values for the different degrees of fibrosis. We enrolled 11 healthy subjects and 48 patients with chronic liver disease. They all performed TE, 33 patients and healthy subjects were evaluated withPoint SWE and 15 patients with 2D-SWE. The differences between techniques and TE, evaluated with student’s t-test, were not statistically significant (p>0,05). The cut-offs of SWE technique were for F≥2 6,2 kPa; F≥3 7,65 kPa; F=4 13 kPa. SWE techniques have good potential in assessing liver fibrosis; moreover, being elastosonography quick and easy to perform, it could be integrated into the clinical practice of the ultrasound examination.
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肝硬化患者肝纤维化的评价:弹性成像与纤维扫描的比较
到目前为止,仍然没有明确的数据表明剪切波弹性成像(SWE)技术在评估肝纤维化方面的有效性。我们的研究旨在比较SWE技术与瞬时弹性成像(TE)获得的肝脏硬度值,并确定不同程度纤维化的阈值。我们招募了11名健康受试者和48名慢性肝病患者。33例患者和健康者采用point SWE, 15例患者采用2D-SWE。技术与TE之间的差异,用学生t检验评估,无统计学意义(p> 0.05)。SWE技术的截止值为F≥2,6,2 kPa;F≥37,65 kPa;F=4 13 kPa。SWE技术在评估肝纤维化方面具有良好的潜力;此外,弹性超声快速、简便,可与临床超声检查相结合。
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