Translational medicine: ways of development in modern conditions, problems and prospects

Abstract

Summary. Introduction The article is devoted to the achievements and prospects of the development of translational medicine at the international level, the state of development, problems and prospects in Ukraine, proposals for improving the system of innovations in health care in modern conditions of martial law. The purpose is to study the development of translational medicine and the prospects for implementing its principles in Ukraine. Materials and methods. To perform the task, an analytical review of publications in the electronic databases of medical and biological publications PubMed Medline of the US National Library of Medicine (NLM), Cochrane Database of Systematic Reviews was conducted. The results. The result of a systematic literature review of the state of translational medicine in Ukraine, which was carried out, is the conviction that the need to create new services and programs that ensure close cooperation between state, commercial and non-commercial organizations of our country, greater accessibility and transparency of new data for all is ripe. Researchers working in the field of broadcasts of inventions. The creation and development of databases with various information on a large number of patients opens wide opportunities for improving the quality of preclinical and clinical trials, and at the same time requires increasing their availability for researchers around the world. It is necessary to increase the use of the potential of social media and/or messengers for the introduction of modern achievements of translational medicine into the clinical practice of our country, the medical community should receive educational programs, recommendations and support infrastructure in social networks. Conclusions. In order to form an effective scientific and educational environment, it is necessary to create a national Institute of Pharmacy and Translational Medicine. It is necessary to create and implement in the educational pharmaceutical space of Ukraine an innovative educational program aimed at training specialists and research personnel of the new generation to work in various branches of the biopharmaceutical industry. It is expedient to create biological models of the use of drugs that allow testing of dose-response effects and to build pharmacokinetic models for specific environmental conditions, which will increase the predictive power of test results during its transition to the stage of clinical trials.