Role of adipose tissue macrophages in obesity-related disorders

S. Chakarov, Camille Blériot, F. Ginhoux
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引用次数: 22

Abstract

As the first immune cells to colonize tissues and long-lived resident cells, macrophages play important roles in tissue functions during early development, homeostasis, and disease. Here, Chakarov et al. discuss macrophage origin and functions in adipose tissue and how these features are modulated in obesity.
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脂肪组织巨噬细胞在肥胖相关疾病中的作用
巨噬细胞作为最早在组织中定植的免疫细胞和长寿的常驻细胞,在早期发育、体内平衡和疾病的组织功能中发挥着重要作用。在这里,Chakarov等人讨论了巨噬细胞在脂肪组织中的起源和功能,以及这些特征如何在肥胖中被调节。
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