Yang Zhang, Y. Ye, Xiaoqiang Tang, Hui Wang, Toshiko Tanaka, R. Tian, Xufei Yang, Lun Wang, Ying Xiao, Xiaomin Hu, Ye Jin, H. Pang, Tian Du, Honghong Liu, Lihong Sun, Shuo Xiao, R. Dong, L. Ferrucci, Z. Tian, Shuyang Zhang
{"title":"CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure","authors":"Yang Zhang, Y. Ye, Xiaoqiang Tang, Hui Wang, Toshiko Tanaka, R. Tian, Xufei Yang, Lun Wang, Ying Xiao, Xiaomin Hu, Ye Jin, H. Pang, Tian Du, Honghong Liu, Lihong Sun, Shuo Xiao, R. Dong, L. Ferrucci, Z. Tian, Shuyang Zhang","doi":"10.1084/jem.20200418","DOIUrl":null,"url":null,"abstract":"Zhang et al. identified chemokine CCL17 as a contributor to age-related heart failure in humans and mice via regulating plasticity and differentiation of T cells. Their findings suggested CCL17 as a novel therapeutic target in age-related heart failure.","PeriodicalId":23015,"journal":{"name":"The Tokushima journal of experimental medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Tokushima journal of experimental medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1084/jem.20200418","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 14
Abstract
Zhang et al. identified chemokine CCL17 as a contributor to age-related heart failure in humans and mice via regulating plasticity and differentiation of T cells. Their findings suggested CCL17 as a novel therapeutic target in age-related heart failure.
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