Metered Dose Inhalers (MDI’S) for High-Performance Pulmonary Drug Delivery in Assistance to Nanotechnology

Manali Harshal Barve, Priti Kiran Shardul, Satish Sundarrao Munne, Atul R. Bendale, V. Naphade, V. Pathan, Laxmikant B. Borse
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Abstract

Respiratory infections pose a severe danger to public health's morbidity and death on a global scale. Delivery via the lungs can be accomplished using several drug delivery tools, including nebulizers, MDI’s and dry powder inhalers. Metered dosage inhalers are the most intriguing and the clinician's first preference out of all of them. This review emphasized based on metered dose inhalers for the delivery of pulmonary drugs. This study focuses on the provision of various therapies employing lipid nanocarriers, polymeric nanoparticles dendrimers & micelles, among others, using metered dose inhalers, liposomes, solid lipid nanostructures, nanostructured lipid carriers, and other topics were thoroughly explored. The market scenario for different MDI’s as well as information on digital metered dose inhalers is also covered in this review.
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辅助纳米技术的高效肺给药计量吸入器(MDI’s)
在全球范围内,呼吸道感染对公共卫生的发病率和死亡率构成严重威胁。通过肺部给药可以使用几种给药工具,包括雾化器、MDI和干粉吸入器。计量吸入器是最有趣的,也是临床医生的首选。本综述着重介绍了用于肺部药物输送的计量吸入器。本研究的重点是提供各种治疗脂质纳米载体,聚合物纳米粒子树突和胶束,其中,使用计量吸入器,脂质体,固体脂质纳米结构,纳米结构脂质载体,和其他主题进行了深入探讨。本综述还介绍了不同MDI的市场情况以及数字计量吸入器的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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