Jing Cao, Xuming Sun, Ru Zhang, Jingyi Huang, Kun Qian
{"title":"Size-selected Core-shell Nanoalloys for Laser Desorption/ionization Detection of Small Metabolites","authors":"Jing Cao, Xuming Sun, Ru Zhang, Jingyi Huang, Kun Qian","doi":"10.1109/3M-NANO.2018.8552252","DOIUrl":null,"url":null,"abstract":"Sensitive and high throughput detection of small metabolites in human biofluid plays an important role in the diagnosis of diseases. Here we report a one-step synthesis of a kind of core-shell nanoalloy with tunable structures for LDI-MS detection of small metabolites. The optimized nanoalloy could detect small molecules in 1.0 microliter biofluid with direct LDI-MS method.","PeriodicalId":6583,"journal":{"name":"2018 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"42 1","pages":"350-353"},"PeriodicalIF":0.0000,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/3M-NANO.2018.8552252","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Sensitive and high throughput detection of small metabolites in human biofluid plays an important role in the diagnosis of diseases. Here we report a one-step synthesis of a kind of core-shell nanoalloy with tunable structures for LDI-MS detection of small metabolites. The optimized nanoalloy could detect small molecules in 1.0 microliter biofluid with direct LDI-MS method.