Advancing Age as a Risk Factor for Acute Myocardial Infarction

Aishat Bashir, A. Salam, Aasia Kanwal
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Abstract

Background: Acute myocardial infarction (AMI) is one of the leading causes of death in developed and developing countries. Age is an important non-modifiable risk factor for acute myocardial infarction. Objectives: The objective of the study was to explore the relationship of advancing age with the risk of acute myocardial infarction. Methods: It was a cross-sectional study conducted in 2019 after getting approval from Institutional Review board of University of Health Sciences, Lahore. Written informed consent and thorough history was taken from the study participants. Group 1 included 45 AMI patients aged 20-60 years. Group 2 included 45 healthy individuals aged 20-60 years. Independent sample t test and chi-square tests were applied for analysis of data. Results: Mean age was significantly higher in AMI patients (50.52±7.31) as compared to healthy controls (30.67±7.20). The risk of AMI increases with advancing age (p<0.001, OR= 2.78). Conclusions: Advancing age is an important risk factor for acute myocardial infarction.
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高龄是急性心肌梗死的危险因素
背景:急性心肌梗死(AMI)是发达国家和发展中国家的主要死亡原因之一。年龄是急性心肌梗死不可改变的重要危险因素。目的:探讨年龄增长与急性心肌梗死风险的关系。方法:经拉合尔健康科学大学机构审查委员会批准,于2019年开展横断面研究。从研究参与者处获取书面知情同意书和详细的病史。1组患者45例,年龄20 ~ 60岁。第二组为45例20 ~ 60岁的健康个体。数据分析采用独立样本t检验和卡方检验。结果:AMI患者的平均年龄(50.52±7.31)明显高于健康对照组(30.67±7.20)。AMI的发生风险随着年龄的增长而增加(p<0.001, OR= 2.78)。结论:高龄是急性心肌梗死的重要危险因素。
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