B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection

E. N. Arroyo, M. Pepper
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引用次数: 29

Abstract

Arroyo and Pepper demonstrate that interactions with B cells, not dendritic cells, are required for the priming of the CD4+ T cell response during Plasmodium infection. This results in a Tfh-biased response as reported by others in both mice and humans.
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B细胞足以启动对疟原虫感染的显性CD4+ Tfh反应
Arroyo和Pepper证明,在疟原虫感染期间,CD4+ T细胞应答的启动需要与B细胞相互作用,而不是树突状细胞。正如其他人在小鼠和人类中报道的那样,这导致了tfh偏倚反应。
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