Xiang Sun, Yu Cui, Haiyun Feng, Haifeng Liu, Xiaolong Liu
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引用次数: 42
Abstract
How DNA methylation–mediated repression is reversed before Foxp3 transcription is unclear. Here, Sun et al. show that the epigenetic regulator Uhrf1, which maintained Foxp3 methylation, is down-regulated by TGF-β signaling and provide novel insight into the epigenetic regulation of Foxp3 during iT reg cell differentiation.
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