A mini review on thiadiazole compounds and their pharmacological interest

Abstract

Various 1,3,4-thiazole derivatives have been reported to exhibit various biological activities. The 1,3,4-thiadiazole derivatives found to have diverse pharmacological activities such as, insecticidal, herbicidal, antiviral, anti-tumor, CNS stimulant, anti-bacterial, antifungal, antiangiogenic, antiglaucoma, antiischemic, and anti-inflammatory, antidepressant, anxiolytic, antiparasitic, antitumor, hypoglycemic, antihypertensive and CNS depressant activities The 1,3,4-Thiadiazoles have also been used in many fields and majority of applications as dyes, lubricants, analytical reagents and agents. The 1,3,4-Thiadiazole analogs are associated with diverse biological activities probably by virtue of toxophoric -N=C-Sgroup. Due to the wide range of applications we have studied thiadiazole derivatives for their biological significances.