Endothelial life discontinues without Erk.

The Tokushima journal of experimental medicine Pub Date : 2019-08-05 Epub Date: 2019-07-18 DOI:10.1084/jem.20191048
Yihai Cao
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Abstract

The mechanism of maintaining vascular endothelial identity and integrity is largely unknown. In this issue of JEM, Ricard et al. (https://doi.org/10.1084/jem.20182151) discover essential roles of ERK1/2 in maintaining endothelial homeostasis and its deletion-related serious defects in multiple tissues and organs.

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没有 Erk,内皮细胞的生命就会中断。
维持血管内皮特性和完整性的机制在很大程度上是未知的。在本期《微生物学报》上,Ricard 等人(https://doi.org/10.1084/jem.20182151)发现了 ERK1/2 在维持血管内皮稳态中的重要作用及其在多个组织和器官中与缺失相关的严重缺陷。
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